| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NPD11_163 | NPD11_334 | NPD11_163 | NPD11_334 | Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Belongs to the pyridoxine kinase family. | 0.540 |
| NPD11_163 | NPD11_924 | NPD11_163 | NPD11_924 | Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase. | 0.540 |
| NPD11_332 | NPD11_333 | NPD11_332 | NPD11_333 | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | ECF-type riboflavin transporter, S component family protein; [S] COG4720 Predicted membrane protein. | 0.444 |
| NPD11_332 | NPD11_334 | NPD11_332 | NPD11_334 | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Belongs to the pyridoxine kinase family. | 0.470 |
| NPD11_333 | NPD11_332 | NPD11_333 | NPD11_332 | ECF-type riboflavin transporter, S component family protein; [S] COG4720 Predicted membrane protein. | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.444 |
| NPD11_333 | NPD11_334 | NPD11_333 | NPD11_334 | ECF-type riboflavin transporter, S component family protein; [S] COG4720 Predicted membrane protein. | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Belongs to the pyridoxine kinase family. | 0.785 |
| NPD11_333 | NPD11_335 | NPD11_333 | NPD11_335 | ECF-type riboflavin transporter, S component family protein; [S] COG4720 Predicted membrane protein. | Hypothetical protein. | 0.526 |
| NPD11_334 | NPD11_163 | NPD11_334 | NPD11_163 | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Belongs to the pyridoxine kinase family. | Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.540 |
| NPD11_334 | NPD11_332 | NPD11_334 | NPD11_332 | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Belongs to the pyridoxine kinase family. | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.470 |
| NPD11_334 | NPD11_333 | NPD11_334 | NPD11_333 | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Belongs to the pyridoxine kinase family. | ECF-type riboflavin transporter, S component family protein; [S] COG4720 Predicted membrane protein. | 0.785 |
| NPD11_334 | NPD11_335 | NPD11_334 | NPD11_335 | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Belongs to the pyridoxine kinase family. | Hypothetical protein. | 0.526 |
| NPD11_334 | NPD11_924 | NPD11_334 | NPD11_924 | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Belongs to the pyridoxine kinase family. | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase. | 0.921 |
| NPD11_334 | pdxS | NPD11_334 | NPD11_2959 | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Belongs to the pyridoxine kinase family. | Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.915 |
| NPD11_334 | pdxT | NPD11_334 | NPD11_2960 | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Belongs to the pyridoxine kinase family. | Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.912 |
| NPD11_335 | NPD11_333 | NPD11_335 | NPD11_333 | Hypothetical protein. | ECF-type riboflavin transporter, S component family protein; [S] COG4720 Predicted membrane protein. | 0.526 |
| NPD11_335 | NPD11_334 | NPD11_335 | NPD11_334 | Hypothetical protein. | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Belongs to the pyridoxine kinase family. | 0.526 |
| NPD11_924 | NPD11_163 | NPD11_924 | NPD11_163 | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase. | Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.540 |
| NPD11_924 | NPD11_334 | NPD11_924 | NPD11_334 | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase. | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Belongs to the pyridoxine kinase family. | 0.921 |
| NPD11_924 | pdxS | NPD11_924 | NPD11_2959 | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase. | Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.915 |
| NPD11_924 | pdxT | NPD11_924 | NPD11_2960 | Phosphomethylpyrimidine kinase family protein; [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase. | Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.912 |