STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIVBspore_IV_B: stage IV sporulation protein B; [M] COG0750 Predicted membrane-associated Zn-dependent proteases 1. (395 aa)    
Predicted Functional Partners:
spo0A
Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
   
 0.974
spoIIIAG
spore_III_AG: stage III sporulation protein AG.
 
     0.856
spoIIIAE
spore_III_AE: stage III sporulation protein AE.
 
   
 0.855
spoIIIAD
spore_III_AD: stage III sporulation protein AD.
 
     0.852
spoIIIAA
spore_III_AA: stage III sporulation protein AA; [S] COG3854 Uncharacterized protein conserved in bacteria.
 
   
 0.844
spoIIP
spore_II_P: stage II sporulation P family protein.
  
   
 0.830
spoIIIAC
spore_III_AC: stage III sporulation protein AC.
 
     0.821
yabP
spore_yabP: sporulation protein YabP.
  
   
 0.818
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.808
spoIIR
spore_II_R: stage II sporulation protein R.
  
   
 0.807
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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