| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NPD11_359 | NPD11_361 | NPD11_359 | NPD11_361 | Tly: TlyA rRNA methyltransferase/hemolysin family protein; [J] COG1189 Predicted rRNA methylase. | Polyprenyl synthetase family protein; [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.912 |
| NPD11_359 | argR | NPD11_359 | NPD11_357 | Tly: TlyA rRNA methyltransferase/hemolysin family protein; [J] COG1189 Predicted rRNA methylase. | Arginine repressor; Regulates arginine biosynthesis genes. | 0.809 |
| NPD11_359 | dxs | NPD11_359 | NPD11_360 | Tly: TlyA rRNA methyltransferase/hemolysin family protein; [J] COG1189 Predicted rRNA methylase. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.897 |
| NPD11_359 | nadK | NPD11_359 | NPD11_358 | Tly: TlyA rRNA methyltransferase/hemolysin family protein; [J] COG1189 Predicted rRNA methylase. | ATP-NAD kinase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.913 |
| NPD11_359 | recN | NPD11_359 | NPD11_356 | Tly: TlyA rRNA methyltransferase/hemolysin family protein; [J] COG1189 Predicted rRNA methylase. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.813 |
| NPD11_361 | NPD11_359 | NPD11_361 | NPD11_359 | Polyprenyl synthetase family protein; [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Tly: TlyA rRNA methyltransferase/hemolysin family protein; [J] COG1189 Predicted rRNA methylase. | 0.912 |
| NPD11_361 | argR | NPD11_361 | NPD11_357 | Polyprenyl synthetase family protein; [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Arginine repressor; Regulates arginine biosynthesis genes. | 0.775 |
| NPD11_361 | dxs | NPD11_361 | NPD11_360 | Polyprenyl synthetase family protein; [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.871 |
| NPD11_361 | nadK | NPD11_361 | NPD11_358 | Polyprenyl synthetase family protein; [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | ATP-NAD kinase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.869 |
| NPD11_361 | recN | NPD11_361 | NPD11_356 | Polyprenyl synthetase family protein; [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.770 |
| argB | argC | NPD11_2600 | NPD11_2602 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.999 |
| argB | argF | NPD11_2600 | NPD11_2598 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.983 |
| argB | argH | NPD11_2600 | NPD11_2603 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | argH: argininosuccinate lyase; [E] COG0165 Argininosuccinate lyase. | 0.975 |
| argB | argJ | NPD11_2600 | NPD11_2601 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.999 |
| argB | argR | NPD11_2600 | NPD11_357 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Arginine repressor; Regulates arginine biosynthesis genes. | 0.809 |
| argC | argB | NPD11_2602 | NPD11_2600 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.999 |
| argC | argF | NPD11_2602 | NPD11_2598 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.959 |
| argC | argH | NPD11_2602 | NPD11_2603 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | argH: argininosuccinate lyase; [E] COG0165 Argininosuccinate lyase. | 0.979 |
| argC | argJ | NPD11_2602 | NPD11_2601 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.992 |
| argC | argR | NPD11_2602 | NPD11_357 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Arginine repressor; Regulates arginine biosynthesis genes. | 0.775 |