| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQM60870.1 | NPD11_398 | NPD11_1747 | NPD11_398 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Multi-copper polyphenol oxidoreductase laccase family protein; [S] COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.904 |
| AQM60870.1 | add | NPD11_1747 | NPD11_4 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Aden_deam: adenosine deaminase; [F] COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | 0.922 |
| AQM60870.1 | deoD | NPD11_1747 | NPD11_699 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | deoD: purine nucleoside phosphorylase; [F] COG0813 Purine-nucleoside phosphorylase. | 0.941 |
| AQM60870.1 | guaA | NPD11_1747 | NPD11_1505 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.676 |
| AQM60870.1 | guaB | NPD11_1747 | NPD11_1506 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.565 |
| NPD11_3 | add | NPD11_3 | NPD11_4 | Small, acid-soluble spore s, alpha/beta type family protein. | Aden_deam: adenosine deaminase; [F] COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | 0.440 |
| NPD11_398 | AQM60870.1 | NPD11_398 | NPD11_1747 | Multi-copper polyphenol oxidoreductase laccase family protein; [S] COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.904 |
| NPD11_398 | add | NPD11_398 | NPD11_4 | Multi-copper polyphenol oxidoreductase laccase family protein; [S] COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family. | Aden_deam: adenosine deaminase; [F] COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | 0.903 |
| NPD11_398 | deoD | NPD11_398 | NPD11_699 | Multi-copper polyphenol oxidoreductase laccase family protein; [S] COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family. | deoD: purine nucleoside phosphorylase; [F] COG0813 Purine-nucleoside phosphorylase. | 0.900 |
| NPD11_5 | add | NPD11_5 | NPD11_4 | Hypothetical protein. | Aden_deam: adenosine deaminase; [F] COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | 0.494 |
| add | AQM60870.1 | NPD11_4 | NPD11_1747 | Aden_deam: adenosine deaminase; [F] COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.922 |
| add | NPD11_3 | NPD11_4 | NPD11_3 | Aden_deam: adenosine deaminase; [F] COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | Small, acid-soluble spore s, alpha/beta type family protein. | 0.440 |
| add | NPD11_398 | NPD11_4 | NPD11_398 | Aden_deam: adenosine deaminase; [F] COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | Multi-copper polyphenol oxidoreductase laccase family protein; [S] COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.903 |
| add | NPD11_5 | NPD11_4 | NPD11_5 | Aden_deam: adenosine deaminase; [F] COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | Hypothetical protein. | 0.494 |
| add | cdd | NPD11_4 | NPD11_2946 | Aden_deam: adenosine deaminase; [F] COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.555 |
| add | deoD | NPD11_4 | NPD11_699 | Aden_deam: adenosine deaminase; [F] COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | deoD: purine nucleoside phosphorylase; [F] COG0813 Purine-nucleoside phosphorylase. | 0.914 |
| add | guaA | NPD11_4 | NPD11_1505 | Aden_deam: adenosine deaminase; [F] COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.723 |
| add | guaB | NPD11_4 | NPD11_1506 | Aden_deam: adenosine deaminase; [F] COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.615 |
| cdd | add | NPD11_2946 | NPD11_4 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Aden_deam: adenosine deaminase; [F] COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | 0.555 |
| cdd | deoD | NPD11_2946 | NPD11_699 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | deoD: purine nucleoside phosphorylase; [F] COG0813 Purine-nucleoside phosphorylase. | 0.460 |