STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcmDcm: DNA (cytosine-5-)-methyltransferase family protein; [L] COG0270 Site-specific DNA methylase. (353 aa)    
Predicted Functional Partners:
NPD11_44
eco47II restriction endonuclease family protein.
   
 0.944
NPD11_798
DEAD/DEAH box helicase family protein; [KL] COG1061 DNA or RNA helicases of superfamily II.
  
  
 0.579
nifJ
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase; [C] COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.
 
 
 
 0.532
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.524
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.492
NPD11_913
dnaJ domain protein; [O] COG2214 DnaJ-class molecular chaperone.
  
 
 0.492
ccmA-2
ccmA: heme ABC exporter, ATP-binding protein CcmA; [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains.
       0.482
AQM60941.1
BRCA1 C Terminus domain protein; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.
     
 0.477
AQM61249.1
Conserved hypothetical protein; [R] COG1988 Predicted membrane-bound metal-dependent hydrolases.
   
    0.476
AQM59238.1
[R] COG0457 FOG: TPR repeat.
     
 0.444
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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