| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NPD11_459 | NPD11_462 | NPD11_459 | NPD11_462 | spore_YlmC_YmxH: sporulation, YlmC/YmxH family protein; [S] COG1873 Uncharacterized conserved protein. | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.853 |
| NPD11_459 | sigE | NPD11_459 | NPD11_461 | spore_YlmC_YmxH: sporulation, YlmC/YmxH family protein; [S] COG1873 Uncharacterized conserved protein. | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.870 |
| NPD11_459 | sigG | NPD11_459 | NPD11_460 | spore_YlmC_YmxH: sporulation, YlmC/YmxH family protein; [S] COG1873 Uncharacterized conserved protein. | RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.902 |
| NPD11_459 | spoIIAB | NPD11_459 | NPD11_2916 | spore_YlmC_YmxH: sporulation, YlmC/YmxH family protein; [S] COG1873 Uncharacterized conserved protein. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.519 |
| NPD11_459 | spoIIE | NPD11_459 | NPD11_1718 | spore_YlmC_YmxH: sporulation, YlmC/YmxH family protein; [S] COG1873 Uncharacterized conserved protein. | spore_II_E: stage II sporulation protein E; [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit. | 0.743 |
| NPD11_459 | spoIIIAE | NPD11_459 | NPD11_370 | spore_YlmC_YmxH: sporulation, YlmC/YmxH family protein; [S] COG1873 Uncharacterized conserved protein. | spore_III_AE: stage III sporulation protein AE. | 0.758 |
| NPD11_459 | spoIIM | NPD11_459 | NPD11_351 | spore_YlmC_YmxH: sporulation, YlmC/YmxH family protein; [S] COG1873 Uncharacterized conserved protein. | spo_II_M: stage II sporulation protein M; [S] COG1300 Uncharacterized membrane protein. | 0.691 |
| NPD11_459 | spoIIP | NPD11_459 | NPD11_2926 | spore_YlmC_YmxH: sporulation, YlmC/YmxH family protein; [S] COG1873 Uncharacterized conserved protein. | spore_II_P: stage II sporulation P family protein. | 0.741 |
| NPD11_459 | spoIIR | NPD11_459 | NPD11_1413 | spore_YlmC_YmxH: sporulation, YlmC/YmxH family protein; [S] COG1873 Uncharacterized conserved protein. | spore_II_R: stage II sporulation protein R. | 0.792 |
| NPD11_459 | yqfD | NPD11_459 | NPD11_2942 | spore_YlmC_YmxH: sporulation, YlmC/YmxH family protein; [S] COG1873 Uncharacterized conserved protein. | spore_yqfD: sporulation protein YqfD. | 0.726 |
| NPD11_462 | NPD11_459 | NPD11_462 | NPD11_459 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | spore_YlmC_YmxH: sporulation, YlmC/YmxH family protein; [S] COG1873 Uncharacterized conserved protein. | 0.853 |
| NPD11_462 | sigE | NPD11_462 | NPD11_461 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.922 |
| NPD11_462 | sigG | NPD11_462 | NPD11_460 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.904 |
| NPD11_462 | spoIIAB | NPD11_462 | NPD11_2916 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.851 |
| NPD11_462 | spoIIE | NPD11_462 | NPD11_1718 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | spore_II_E: stage II sporulation protein E; [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit. | 0.940 |
| NPD11_462 | spoIIIAE | NPD11_462 | NPD11_370 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | spore_III_AE: stage III sporulation protein AE. | 0.776 |
| NPD11_462 | spoIIM | NPD11_462 | NPD11_351 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | spo_II_M: stage II sporulation protein M; [S] COG1300 Uncharacterized membrane protein. | 0.789 |
| NPD11_462 | spoIIP | NPD11_462 | NPD11_2926 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | spore_II_P: stage II sporulation P family protein. | 0.805 |
| NPD11_462 | spoIIR | NPD11_462 | NPD11_1413 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | spore_II_R: stage II sporulation protein R. | 0.839 |
| NPD11_462 | yqfD | NPD11_462 | NPD11_2942 | Sporulation factor SpoIIGA family protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | spore_yqfD: sporulation protein YqfD. | 0.812 |
