| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| sigK | spo0A | NPD11_467 | NPD11_354 | RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.860 |
| sigK | spoIIAB | NPD11_467 | NPD11_2916 | RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.762 |
| sigK | spoIIID | NPD11_467 | NPD11_1382 | RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | spore_III_D: sporulation transcriptional regulator SpoIIID. | 0.776 |
| sigK | spoIVA | NPD11_467 | NPD11_172 | RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.774 |
| sigK | spoIVB | NPD11_467 | NPD11_355 | RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | spore_IV_B: stage IV sporulation protein B; [M] COG0750 Predicted membrane-associated Zn-dependent proteases 1. | 0.787 |
| sigK | spoVAC | NPD11_467 | NPD11_2919 | RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | spore_V_AC: stage V sporulation protein AC. | 0.772 |
| sigK | spoVAD | NPD11_467 | NPD11_2920 | RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | spore_V_AD: stage V sporulation protein AD. | 0.771 |
| sigK | spoVAE | NPD11_467 | NPD11_2921 | RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | spore_V_AE: stage V sporulation protein AE. | 0.770 |
| sigK | spoVT | NPD11_467 | NPD11_1734 | RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | spore_V_T: stage V sporulation protein T; [K] COG2002 Regulators of stationary/sporulation gene expression. | 0.764 |
| sigK | yqfD | NPD11_467 | NPD11_2942 | RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | spore_yqfD: sporulation protein YqfD. | 0.780 |
| spo0A | sigK | NPD11_354 | NPD11_467 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.860 |
| spo0A | spoIIAB | NPD11_354 | NPD11_2916 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.866 |
| spo0A | spoIIID | NPD11_354 | NPD11_1382 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | spore_III_D: sporulation transcriptional regulator SpoIIID. | 0.862 |
| spo0A | spoIVA | NPD11_354 | NPD11_172 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.856 |
| spo0A | spoIVB | NPD11_354 | NPD11_355 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | spore_IV_B: stage IV sporulation protein B; [M] COG0750 Predicted membrane-associated Zn-dependent proteases 1. | 0.964 |
| spo0A | spoVAC | NPD11_354 | NPD11_2919 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | spore_V_AC: stage V sporulation protein AC. | 0.774 |
| spo0A | spoVAD | NPD11_354 | NPD11_2920 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | spore_V_AD: stage V sporulation protein AD. | 0.817 |
| spo0A | spoVAE | NPD11_354 | NPD11_2921 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | spore_V_AE: stage V sporulation protein AE. | 0.748 |
| spo0A | spoVT | NPD11_354 | NPD11_1734 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | spore_V_T: stage V sporulation protein T; [K] COG2002 Regulators of stationary/sporulation gene expression. | 0.824 |
| spo0A | yqfD | NPD11_354 | NPD11_2942 | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | spore_yqfD: sporulation protein YqfD. | 0.691 |
