node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NPD11_501 | NPD11_504 | NPD11_501 | NPD11_504 | Dihydroorotate dehydrogenase family protein; [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase. | Cullin neddylation domain protein; [K] COG1846 Transcriptional regulators. | 0.687 |
NPD11_501 | accA | NPD11_501 | NPD11_493 | Dihydroorotate dehydrogenase family protein; [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase. | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 0.794 |
NPD11_501 | accC | NPD11_501 | NPD11_495 | Dihydroorotate dehydrogenase family protein; [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase. | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.795 |
NPD11_501 | accD | NPD11_501 | NPD11_494 | Dihydroorotate dehydrogenase family protein; [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase. | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | 0.855 |
NPD11_501 | acpP-2 | NPD11_501 | NPD11_502 | Dihydroorotate dehydrogenase family protein; [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase. | Phosphopantetheine attachment site family protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.758 |
NPD11_501 | fabD | NPD11_501 | NPD11_500 | Dihydroorotate dehydrogenase family protein; [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase. | fabD: malonyl CoA-acyl carrier protein transacylase; [I] COG0331 (acyl-carrier-protein) S-malonyltransferase. | 0.946 |
NPD11_501 | fabF | NPD11_501 | NPD11_498 | Dihydroorotate dehydrogenase family protein; [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase. | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.992 |
NPD11_501 | fabG | NPD11_501 | NPD11_499 | Dihydroorotate dehydrogenase family protein; [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase. | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.906 |
NPD11_501 | fabH | NPD11_501 | NPD11_503 | Dihydroorotate dehydrogenase family protein; [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase. | 3-oxoacyl-[acyl-carrier-] synthase III family protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.681 |
NPD11_501 | fabZ | NPD11_501 | NPD11_496 | Dihydroorotate dehydrogenase family protein; [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.986 |
NPD11_504 | NPD11_501 | NPD11_504 | NPD11_501 | Cullin neddylation domain protein; [K] COG1846 Transcriptional regulators. | Dihydroorotate dehydrogenase family protein; [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase. | 0.687 |
NPD11_504 | accA | NPD11_504 | NPD11_493 | Cullin neddylation domain protein; [K] COG1846 Transcriptional regulators. | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 0.637 |
NPD11_504 | accC | NPD11_504 | NPD11_495 | Cullin neddylation domain protein; [K] COG1846 Transcriptional regulators. | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.637 |
NPD11_504 | accD | NPD11_504 | NPD11_494 | Cullin neddylation domain protein; [K] COG1846 Transcriptional regulators. | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | 0.689 |
NPD11_504 | acpP-2 | NPD11_504 | NPD11_502 | Cullin neddylation domain protein; [K] COG1846 Transcriptional regulators. | Phosphopantetheine attachment site family protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.753 |
NPD11_504 | fabD | NPD11_504 | NPD11_500 | Cullin neddylation domain protein; [K] COG1846 Transcriptional regulators. | fabD: malonyl CoA-acyl carrier protein transacylase; [I] COG0331 (acyl-carrier-protein) S-malonyltransferase. | 0.732 |
NPD11_504 | fabF | NPD11_504 | NPD11_498 | Cullin neddylation domain protein; [K] COG1846 Transcriptional regulators. | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.729 |
NPD11_504 | fabG | NPD11_504 | NPD11_499 | Cullin neddylation domain protein; [K] COG1846 Transcriptional regulators. | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.669 |
NPD11_504 | fabH | NPD11_504 | NPD11_503 | Cullin neddylation domain protein; [K] COG1846 Transcriptional regulators. | 3-oxoacyl-[acyl-carrier-] synthase III family protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.881 |
NPD11_504 | fabZ | NPD11_504 | NPD11_496 | Cullin neddylation domain protein; [K] COG1846 Transcriptional regulators. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.710 |