STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPD11_580Malic enzyme, NAD binding domain protein; [C] COG0281 Malic enzyme. (544 aa)    
Predicted Functional Partners:
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 0.944
ldh-2
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.944
AQM58749.1
ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate, Fe-S type domain protein; [C] COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.
  
 
 0.938
AQM61154.1
ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate, Fe-S type domain protein; [C] COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.
  
 
 0.938
AQM60295.1
Hypothetical protein.
    
 0.907
lpdA
lipoamide_DH: dihydrolipoyl dehydrogenase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
  
  
 0.839
AQM59376.1
Membrane transport family protein; [R] COG0679 Predicted permeases.
  
  
 0.759
nifJ
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase; [C] COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.
  
  
 0.644
pyk
Pyruv_kin: pyruvate kinase; [G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.577
pyk-2
Pyruv_kin: pyruvate kinase; [G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.577
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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