| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQM58747.1 | NPD11_658 | NPD11_1429 | NPD11_658 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | carD-like/TRCF domain protein; [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD. | 0.458 |
| AQM61474.1 | NPD11_658 | NPD11_2760 | NPD11_658 | NADH:flavin oxidoreductase / NADH oxidase family protein; [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | carD-like/TRCF domain protein; [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD. | 0.535 |
| AQM61474.1 | ispH | NPD11_2760 | NPD11_311 | NADH:flavin oxidoreductase / NADH oxidase family protein; [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.533 |
| NPD11_657 | NPD11_658 | NPD11_657 | NPD11_658 | Hypothetical protein; Glycosyl hydrolase family 3 N terminal domain protein; [G] COG1472 Beta-glucosidase-related glycosidases. | carD-like/TRCF domain protein; [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD. | 0.519 |
| NPD11_658 | AQM58747.1 | NPD11_658 | NPD11_1429 | carD-like/TRCF domain protein; [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD. | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | 0.458 |
| NPD11_658 | AQM61474.1 | NPD11_658 | NPD11_2760 | carD-like/TRCF domain protein; [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD. | NADH:flavin oxidoreductase / NADH oxidase family protein; [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.535 |
| NPD11_658 | NPD11_657 | NPD11_658 | NPD11_657 | carD-like/TRCF domain protein; [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD. | Hypothetical protein; Glycosyl hydrolase family 3 N terminal domain protein; [G] COG1472 Beta-glucosidase-related glycosidases. | 0.519 |
| NPD11_658 | ispH | NPD11_658 | NPD11_311 | carD-like/TRCF domain protein; [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.435 |
| NPD11_658 | rex | NPD11_658 | NPD11_1531 | carD-like/TRCF domain protein; [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD. | Oxidoreductase, NAD-binding Rossmann fold family protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.458 |
| NPD11_658 | rpoA | NPD11_658 | NPD11_1619 | carD-like/TRCF domain protein; [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.860 |
| NPD11_658 | rpoB | NPD11_658 | NPD11_1655 | carD-like/TRCF domain protein; [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.874 |
| NPD11_658 | rpoC | NPD11_658 | NPD11_1654 | carD-like/TRCF domain protein; [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.874 |
| NPD11_658 | rpoD | NPD11_658 | NPD11_2955 | carD-like/TRCF domain protein; [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.873 |
| NPD11_658 | rpoZ | NPD11_658 | NPD11_179 | carD-like/TRCF domain protein; [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.876 |
| ispH | AQM61474.1 | NPD11_311 | NPD11_2760 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | NADH:flavin oxidoreductase / NADH oxidase family protein; [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.533 |
| ispH | NPD11_658 | NPD11_311 | NPD11_658 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | carD-like/TRCF domain protein; [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD. | 0.435 |
| ispH | rpoA | NPD11_311 | NPD11_1619 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.820 |
| ispH | rpoB | NPD11_311 | NPD11_1655 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.817 |
| ispH | rpoC | NPD11_311 | NPD11_1654 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.837 |
| ispH | rpoD | NPD11_311 | NPD11_2955 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.423 |