Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NPD11_67N-6 DNA Methylase family protein; [V] COG0286 Type I restriction-modification system methyltransferase subunit. (428 aa)    
Predicted Functional Partners:
NPD11_68
Pseudouridine synthase family protein; [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.
       0.655
AQM59166.1
Conserved hypothetical protein; [R] COG1451 Predicted metal-dependent hydrolase.
 
     0.627
NPD11_69
[L] COG1041 Predicted DNA modification methylase.
       0.596
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.588
NPD11_798
DEAD/DEAH box helicase family protein; [KL] COG1061 DNA or RNA helicases of superfamily II.
     
 0.534
NPD11_70
3mg: DNA-3-methyladenine glycosylase family protein; [L] COG2094 3-methyladenine DNA glycosylase; Belongs to the DNA glycosylase MPG family.
       0.532
NPD11_388
[K] COG1293 Predicted RNA-binding protein homologous to eukaryotic snRNP.
  
    0.496
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
  
 
 
 0.493
NPD11_65
Putative histamine N-methyltransferase.
       0.477
NPD11_66
Hypothetical protein.
       0.477
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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