Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NPD11_676pfkB carbohydrate kinase family protein; [G] COG0524 Sugar kinases, ribokinase family; Belongs to the carbohydrate kinase PfkB family. (314 aa)    
Predicted Functional Partners:
NPD11_677
Sucrose-6-phosphate hydrolase family protein; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
 
 0.997
fruA
fruA: PTS system, fructose subfamily, IIA component domain protein; [G] COG1299 Phosphotransferase system, fructose-specific IIC component.
    
 0.936
pgi
Phosphoglucose isomerase family protein; [G] COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 
 0.926
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
  
 
 0.916
fruA-2
fruA: PTS system, fructose subfamily, IIA component domain protein; [G] COG1299 Phosphotransferase system, fructose-specific IIC component.
     
 0.914
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 0.911
AQM60579.1
[G] COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; Belongs to the glycosyl hydrolase 31 family.
  
 
 0.911
pfp
Phosphofructokinase family protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 0.911
pfkA1
Phosphofructokinase family protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
 0.911
manA
manA: mannose-6-phosphate isomerase, class I; [G] COG1482 Phosphomannose isomerase.
    
 0.908
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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