STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPD11_678Helix-turn-helix family protein; [K] COG1609 Transcriptional regulators. (326 aa)    
Predicted Functional Partners:
NPD11_677
Sucrose-6-phosphate hydrolase family protein; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
 
  
 0.765
NPD11_676
pfkB carbohydrate kinase family protein; [G] COG0524 Sugar kinases, ribokinase family; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.759
NPD11_679
PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component; [G] COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
 
  
 0.735
ptsH
Phosphocarrier protein HPr; [G] COG1925 Phosphotransferase system, HPr-related proteins.
   
 
 0.554
NPD11_267
AAA domain family protein; [KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains.
   
 
 0.539
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.457
AQM59169.1
UTRA domain protein; [K] COG2188 Transcriptional regulators.
  
   
 0.455
codY
GTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
    
 
 0.455
NPD11_741
UTRA domain protein; [K] COG2188 Transcriptional regulators.
  
   
 0.445
fruA
fruA: PTS system, fructose subfamily, IIA component domain protein; [G] COG1299 Phosphotransferase system, fructose-specific IIC component.
     
 0.442
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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