| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQM59118.1 | NPD11_738 | NPD11_2302 | NPD11_738 | 4Fe-4S binding domain protein; [C] COG0778 Nitroreductase. | NADP-dependent 7-alpha-hydroxysteroid dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.564 |
| AQM59118.1 | lpdA | NPD11_2302 | NPD11_897 | 4Fe-4S binding domain protein; [C] COG0778 Nitroreductase. | lipoamide_DH: dihydrolipoyl dehydrogenase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.835 |
| AQM60391.1 | NPD11_738 | NPD11_2355 | NPD11_738 | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | NADP-dependent 7-alpha-hydroxysteroid dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.507 |
| NPD11_539 | NPD11_738 | NPD11_539 | NPD11_738 | Glycosyl hydrolases 2 family protein; [G] COG3250 Beta-galactosidase/beta-glucuronidase. | NADP-dependent 7-alpha-hydroxysteroid dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.500 |
| NPD11_539 | pfkB | NPD11_539 | NPD11_1367 | Glycosyl hydrolases 2 family protein; [G] COG3250 Beta-galactosidase/beta-glucuronidase. | pfkB: 1-phosphofructokinase; [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.575 |
| NPD11_539 | pfkB-2 | NPD11_539 | NPD11_828 | Glycosyl hydrolases 2 family protein; [G] COG3250 Beta-galactosidase/beta-glucuronidase. | pfkB: 1-phosphofructokinase; [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.575 |
| NPD11_737 | NPD11_738 | NPD11_737 | NPD11_738 | hisJ_fam: histidinol phosphate phosphatase, HisJ family protein; [ER] COG1387 Histidinol phosphatase and related hydrolases of the PHP family; Belongs to the PHP hydrolase family. HisK subfamily. | NADP-dependent 7-alpha-hydroxysteroid dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.477 |
| NPD11_738 | AQM59118.1 | NPD11_738 | NPD11_2302 | NADP-dependent 7-alpha-hydroxysteroid dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 4Fe-4S binding domain protein; [C] COG0778 Nitroreductase. | 0.564 |
| NPD11_738 | AQM60391.1 | NPD11_738 | NPD11_2355 | NADP-dependent 7-alpha-hydroxysteroid dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.507 |
| NPD11_738 | NPD11_539 | NPD11_738 | NPD11_539 | NADP-dependent 7-alpha-hydroxysteroid dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Glycosyl hydrolases 2 family protein; [G] COG3250 Beta-galactosidase/beta-glucuronidase. | 0.500 |
| NPD11_738 | NPD11_737 | NPD11_738 | NPD11_737 | NADP-dependent 7-alpha-hydroxysteroid dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | hisJ_fam: histidinol phosphate phosphatase, HisJ family protein; [ER] COG1387 Histidinol phosphatase and related hydrolases of the PHP family; Belongs to the PHP hydrolase family. HisK subfamily. | 0.477 |
| NPD11_738 | fabD | NPD11_738 | NPD11_500 | NADP-dependent 7-alpha-hydroxysteroid dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | fabD: malonyl CoA-acyl carrier protein transacylase; [I] COG0331 (acyl-carrier-protein) S-malonyltransferase. | 0.609 |
| NPD11_738 | fabF | NPD11_738 | NPD11_498 | NADP-dependent 7-alpha-hydroxysteroid dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.605 |
| NPD11_738 | lpdA | NPD11_738 | NPD11_897 | NADP-dependent 7-alpha-hydroxysteroid dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | lipoamide_DH: dihydrolipoyl dehydrogenase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.598 |
| NPD11_738 | pfkB | NPD11_738 | NPD11_1367 | NADP-dependent 7-alpha-hydroxysteroid dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | pfkB: 1-phosphofructokinase; [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.497 |
| NPD11_738 | pfkB-2 | NPD11_738 | NPD11_828 | NADP-dependent 7-alpha-hydroxysteroid dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | pfkB: 1-phosphofructokinase; [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.497 |
| NPD11_738 | polA | NPD11_738 | NPD11_1018 | NADP-dependent 7-alpha-hydroxysteroid dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.481 |
| fabD | NPD11_738 | NPD11_500 | NPD11_738 | fabD: malonyl CoA-acyl carrier protein transacylase; [I] COG0331 (acyl-carrier-protein) S-malonyltransferase. | NADP-dependent 7-alpha-hydroxysteroid dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.609 |
| fabD | fabF | NPD11_500 | NPD11_498 | fabD: malonyl CoA-acyl carrier protein transacylase; [I] COG0331 (acyl-carrier-protein) S-malonyltransferase. | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.999 |
| fabD | lpdA | NPD11_500 | NPD11_897 | fabD: malonyl CoA-acyl carrier protein transacylase; [I] COG0331 (acyl-carrier-protein) S-malonyltransferase. | lipoamide_DH: dihydrolipoyl dehydrogenase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.445 |