| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQM59346.1 | AQM60919.1 | NPD11_1352 | NPD11_1271 | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | [C] COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | 0.824 |
| AQM59346.1 | NPD11_827 | NPD11_1352 | NPD11_827 | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | 0.900 |
| AQM59346.1 | gapN | NPD11_1352 | NPD11_1592 | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; [C] COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | 0.824 |
| AQM59346.1 | pfkA | NPD11_1352 | NPD11_2243 | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.923 |
| AQM59346.1 | pfkA1 | NPD11_1352 | NPD11_990 | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | Phosphofructokinase family protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.923 |
| AQM59346.1 | pfkB-2 | NPD11_1352 | NPD11_828 | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | pfkB: 1-phosphofructokinase; [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.504 |
| AQM59346.1 | pfp | NPD11_1352 | NPD11_2862 | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | Phosphofructokinase family protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.925 |
| AQM59346.1 | pgk | NPD11_1352 | NPD11_2664 | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | [G] COG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.761 |
| AQM60919.1 | AQM59346.1 | NPD11_1271 | NPD11_1352 | [C] COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | 0.824 |
| AQM60919.1 | NPD11_827 | NPD11_1271 | NPD11_827 | [C] COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | 0.824 |
| AQM60919.1 | gapN | NPD11_1271 | NPD11_1592 | [C] COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; [C] COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | 0.901 |
| AQM60919.1 | pgk | NPD11_1271 | NPD11_2664 | [C] COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | [G] COG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.930 |
| NPD11_827 | AQM59346.1 | NPD11_827 | NPD11_1352 | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | 0.900 |
| NPD11_827 | AQM60919.1 | NPD11_827 | NPD11_1271 | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | [C] COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | 0.824 |
| NPD11_827 | gapN | NPD11_827 | NPD11_1592 | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; [C] COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | 0.824 |
| NPD11_827 | lacA-2 | NPD11_827 | NPD11_825 | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | Galactose-6-phosphate isomerase, LacA subunit; [G] COG0698 Ribose 5-phosphate isomerase RpiB. | 0.782 |
| NPD11_827 | lacB-2 | NPD11_827 | NPD11_826 | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | Galactose-6-phosphate isomerase, LacB subunit; [G] COG0698 Ribose 5-phosphate isomerase RpiB. | 0.803 |
| NPD11_827 | pfkA | NPD11_827 | NPD11_2243 | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.923 |
| NPD11_827 | pfkA1 | NPD11_827 | NPD11_990 | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | Phosphofructokinase family protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.923 |
| NPD11_827 | pfkB-2 | NPD11_827 | NPD11_828 | Tag_bisphos_ald: class II aldolase, tagatose bisphosphate family; [G] COG0191 Fructose/tagatose bisphosphate aldolase. | pfkB: 1-phosphofructokinase; [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.864 |