node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AQM61380.1 | NPD11_91 | NPD11_2585 | NPD11_91 | CM_mono_grmpos: chorismate mutase; [E] COG0077 Prephenate dehydratase. | Calcineurin-like phosphoesterase superfamily domain protein; [S] COG2908 Uncharacterized protein conserved in bacteria. | 0.426 |
AQM61380.1 | glyA | NPD11_2585 | NPD11_90 | CM_mono_grmpos: chorismate mutase; [E] COG0077 Prephenate dehydratase. | Beta-eliminating lyase family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.519 |
NPD11_91 | AQM61380.1 | NPD11_91 | NPD11_2585 | Calcineurin-like phosphoesterase superfamily domain protein; [S] COG2908 Uncharacterized protein conserved in bacteria. | CM_mono_grmpos: chorismate mutase; [E] COG0077 Prephenate dehydratase. | 0.426 |
NPD11_91 | NPD11_92 | NPD11_91 | NPD11_92 | Calcineurin-like phosphoesterase superfamily domain protein; [S] COG2908 Uncharacterized protein conserved in bacteria. | Membrane dipeptidase family protein; [E] COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog. | 0.727 |
NPD11_91 | NPD11_93 | NPD11_91 | NPD11_93 | Calcineurin-like phosphoesterase superfamily domain protein; [S] COG2908 Uncharacterized protein conserved in bacteria. | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.724 |
NPD11_91 | glyA | NPD11_91 | NPD11_90 | Calcineurin-like phosphoesterase superfamily domain protein; [S] COG2908 Uncharacterized protein conserved in bacteria. | Beta-eliminating lyase family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.517 |
NPD11_92 | NPD11_91 | NPD11_92 | NPD11_91 | Membrane dipeptidase family protein; [E] COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog. | Calcineurin-like phosphoesterase superfamily domain protein; [S] COG2908 Uncharacterized protein conserved in bacteria. | 0.727 |
NPD11_92 | NPD11_93 | NPD11_92 | NPD11_93 | Membrane dipeptidase family protein; [E] COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog. | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.836 |
NPD11_92 | glyA | NPD11_92 | NPD11_90 | Membrane dipeptidase family protein; [E] COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog. | Beta-eliminating lyase family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.497 |
NPD11_93 | NPD11_91 | NPD11_93 | NPD11_91 | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Calcineurin-like phosphoesterase superfamily domain protein; [S] COG2908 Uncharacterized protein conserved in bacteria. | 0.724 |
NPD11_93 | NPD11_92 | NPD11_93 | NPD11_92 | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Membrane dipeptidase family protein; [E] COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog. | 0.836 |
NPD11_93 | glyA | NPD11_93 | NPD11_90 | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Beta-eliminating lyase family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.470 |
glyA | AQM61380.1 | NPD11_90 | NPD11_2585 | Beta-eliminating lyase family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | CM_mono_grmpos: chorismate mutase; [E] COG0077 Prephenate dehydratase. | 0.519 |
glyA | NPD11_91 | NPD11_90 | NPD11_91 | Beta-eliminating lyase family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Calcineurin-like phosphoesterase superfamily domain protein; [S] COG2908 Uncharacterized protein conserved in bacteria. | 0.517 |
glyA | NPD11_92 | NPD11_90 | NPD11_92 | Beta-eliminating lyase family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Membrane dipeptidase family protein; [E] COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog. | 0.497 |
glyA | NPD11_93 | NPD11_90 | NPD11_93 | Beta-eliminating lyase family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.470 |