Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NPD11_96Insulinase family protein; [R] COG0612 Predicted Zn-dependent peptidases; Belongs to the peptidase M16 family. (414 aa)    
Predicted Functional Partners:
recX
recX family protein; Modulates RecA activity; Belongs to the RecX family.
 
    0.918
AQM60247.1
FAD dependent oxidoreductase family protein; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).
   
 0.830
NPD11_98
Transglutaminase-like superfamily protein; [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases.
       0.815
NPD11_846
4Fe-4S binding domain protein; [C] COG1145 Ferredoxin.
   
 0.788
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
   
 0.760
atpH
ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
   
 0.752
AQM59118.1
4Fe-4S binding domain protein; [C] COG0778 Nitroreductase.
  
 
 0.752
atpG
ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
   
 0.671
NPD11_95
Hypothetical protein; Transcriptional regulatory, C terminal family protein; [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
   
   0.661
NPD11_94
HAMP domain protein; [T] COG0642 Signal transduction histidine kinase.
       0.653
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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