STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPD11_9773'-5' exonuclease family protein; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. (205 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.962
dnaE
Polc: DNA polymerase III, alpha subunit; [L] COG0587 DNA polymerase III, alpha subunit.
   
 0.962
AQM58986.1
ATPase associated with various cellular activities family protein; [L] COG2812 DNA polymerase III, gamma/tau subunits.
  
 0.956
dnaX
DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.951
holA
holA: DNA polymerase III, delta subunit; [L] COG1466 DNA polymerase III, delta subunit.
  
 
 0.948
AQM60941.1
BRCA1 C Terminus domain protein; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.
 
  
 0.932
polC
DNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
 0.910
NPD11_99
Tetratricopeptide repeat family protein; [R] COG0457 FOG: TPR repeat.
 
     0.780
AQM60048.1
Conserved hypothetical protein; [J] COG2868 Predicted ribosomal protein.
  
     0.766
AQM59686.1
Glucose / Sorbosone dehydrogenase family protein.
  
     0.762
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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