STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pflBPyr_form_ly_1: formate acetyltransferase; [C] COG1882 Pyruvate-formate lyase. (743 aa)    
Predicted Functional Partners:
pflA
Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
  
 0.985
nifJ
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase; [C] COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.
    
 0.971
pta
Pta: phosphate acetyltransferase; [C] COG0280 Phosphotransacetylase.
   
 
 0.938
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
   
 
 0.936
ldh-2
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
   
 
 0.936
AQM58966.1
2-oxoacid:acceptor oxidoreductase, alpha subunit; OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit; [C] COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
    
 0.934
thlA
[I] COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.933
AQM60885.1
Hypothetical protein; acyl-CoA dehydrogenase, N-terminal domain protein; [I] COG1960 Acyl-CoA dehydrogenases.
     
 0.930
pyk
Pyruv_kin: pyruvate kinase; [G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.918
pyk-2
Pyruv_kin: pyruvate kinase; [G] COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.918
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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