STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
manAmanA: mannose-6-phosphate isomerase, class I; [G] COG1482 Phosphomannose isomerase. (326 aa)    
Predicted Functional Partners:
pgi
Phosphoglucose isomerase family protein; [G] COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 
 0.943
AQM59773.1
EIIA-man: PTS system, mannose/fructose/sorbose family, IIA component domain protein; [G] COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB.
 
  
 0.940
pfkA1
Phosphofructokinase family protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
    
 0.934
AQM59657.1
PTS system sorbose-specific iic component family protein; [G] COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC.
 
  
  0.921
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
     
 0.919
AQM60748.1
EIID-AGA: PTS system, mannose/fructose/sorbose, IID component family protein; [G] COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID.
 
  
  0.917
glmS
Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.916
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
     
 0.909
pfp
Phosphofructokinase family protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
     
 0.909
AQM58916.1
[G] COG2893 Phosphotransferase system, mannose/fructose-specific component IIA.
    
 0.907
Your Current Organism:
Clostridium baratii
NCBI taxonomy Id: 1561
Other names: ATCC 27638, Acuformis perennis, BCRC 14541, C. baratii, CCRC 14541, CCRC:14541, CCUG 24033, CIP 104306, Clostridium barati, Clostridium paraperfringens, Clostridium perenne, DSM 601, Inflabilis barati
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