node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NY78_0607 | NY78_1999 | NY78_0607 | NY78_1999 | Flagellar motor switch protein FliM. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.831 |
NY78_0607 | NY78_2512 | NY78_0607 | NY78_2512 | Flagellar motor switch protein FliM. | Lactoylglutation lyase. | 0.751 |
NY78_0607 | NY78_3599 | NY78_0607 | NY78_3599 | Flagellar motor switch protein FliM. | Pyruvate-flavodoxin oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. | 0.499 |
NY78_0607 | nuoB | NY78_0607 | NY78_1394 | Flagellar motor switch protein FliM. | NADH-ubiquinone oxidoreductase chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. | 0.411 |
NY78_0880 | NY78_1940 | NY78_0880 | NY78_1940 | Beta-lactamase domain protein. | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.787 |
NY78_0880 | NY78_1999 | NY78_0880 | NY78_1999 | Beta-lactamase domain protein. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.834 |
NY78_0880 | NY78_2512 | NY78_0880 | NY78_2512 | Beta-lactamase domain protein. | Lactoylglutation lyase. | 0.750 |
NY78_0880 | nuoB | NY78_0880 | NY78_1394 | Beta-lactamase domain protein. | NADH-ubiquinone oxidoreductase chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. | 0.403 |
NY78_0880 | sucD | NY78_0880 | NY78_1732 | Beta-lactamase domain protein. | Succinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.442 |
NY78_1498 | NY78_1940 | NY78_1498 | NY78_1940 | NAD-reducing hydrogenase subunit HoxF. | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.764 |
NY78_1498 | NY78_1999 | NY78_1498 | NY78_1999 | NAD-reducing hydrogenase subunit HoxF. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.873 |
NY78_1498 | NY78_2512 | NY78_1498 | NY78_2512 | NAD-reducing hydrogenase subunit HoxF. | Lactoylglutation lyase. | 0.836 |
NY78_1498 | NY78_3419 | NY78_1498 | NY78_3419 | NAD-reducing hydrogenase subunit HoxF. | 2-oxoglutarate oxidoreductase, alpha subunit. | 0.984 |
NY78_1498 | NY78_3463 | NY78_1498 | NY78_3463 | NAD-reducing hydrogenase subunit HoxF. | NAD-reducing hydrogenase subunit HoxF. | 0.999 |
NY78_1498 | NY78_3599 | NY78_1498 | NY78_3599 | NAD-reducing hydrogenase subunit HoxF. | Pyruvate-flavodoxin oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. | 0.999 |
NY78_1498 | nuoB | NY78_1498 | NY78_1394 | NAD-reducing hydrogenase subunit HoxF. | NADH-ubiquinone oxidoreductase chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. | 0.999 |
NY78_1498 | sucD | NY78_1498 | NY78_1732 | NAD-reducing hydrogenase subunit HoxF. | Succinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.995 |
NY78_1940 | NY78_0880 | NY78_1940 | NY78_0880 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Beta-lactamase domain protein. | 0.787 |
NY78_1940 | NY78_1498 | NY78_1940 | NY78_1498 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | NAD-reducing hydrogenase subunit HoxF. | 0.764 |
NY78_1940 | NY78_1999 | NY78_1940 | NY78_1999 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.844 |