STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEA15972.1Hypothetical protein; Family membership. (384 aa)    
Predicted Functional Partners:
CEA15971.1
Hypothetical protein; Family membership; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.834
CEA14966.1
Sigma-70 family protein; Sigma70 family of sigma factors are components of the RNA polymerase holoenzyme that direct bacterial or plastid core RNA polymerase to specific promoter elements; High confidence in function and specificity; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.710
CEA14964.1
TonB-linked outer membrane protein, SusC/RagA family; Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores [Transport and binding proteins, Unknown substrate]; Family membership.
 
  
 0.698
CEA15339.1
Hypothetical protein; High confidence in function and specificity.
 
  
 0.670
CEA15105.1
Hypothetical protein; Family membership; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.639
CEA15421.1
Putative ECF-type RNA polymerase sigma factor; High confidence in function and specificity; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.628
CEA15241.1
Putative secreted protein.
 
  
 0.625
CEA15973.1
TonB-dependent receptor; High confidence in function and specificity.
 
  
 0.616
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.594
CEA15970.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.594
Your Current Organism:
Fermentimonas caenicola
NCBI taxonomy Id: 1562970
Other names: CECT 8609, DSM 28696, F. caenicola, Fermentimonas caenicola Hahnke et al. 2016, LMG 28429, LMG:28429, Porphyromonadaceae bacterium ING2-E5B, strain E5B, strain ING2-E5B
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.