STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ileSIsoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1139 aa)    
Predicted Functional Partners:
proS
Proline-tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
  
 0.983
argS
Arginine-tRNA ligase; High confidence in function and specificity.
 
 0.960
pheT
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; High confidence in function and specificity; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
 
 0.955
metG
Methionine-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 0.939
gltX
Glutamate-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
 
 0.905
leuS
Leucine-tRNA ligase; High confidence in function and specificity; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.891
glnS
Glutamine-tRNA ligase; High confidence in function and specificity.
 
 0.877
lysS
Lysine-tRNA ligase; High confidence in function and specificity; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 0.827
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
  
 0.799
asnS
Asparagine-tRNA ligase; High confidence in function and specificity.
  
 0.787
Your Current Organism:
Fermentimonas caenicola
NCBI taxonomy Id: 1562970
Other names: CECT 8609, DSM 28696, F. caenicola, Fermentimonas caenicola Hahnke et al. 2016, LMG 28429, LMG:28429, Porphyromonadaceae bacterium ING2-E5B, strain E5B, strain ING2-E5B
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