STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgiGlucose-6-phosphate isomerase; High confidence in function and specificity; Belongs to the GPI family. (449 aa)    
Predicted Functional Partners:
CEA16120.1
Hypothetical protein; High confidence in function and specificity; Belongs to the transketolase family.
  
 0.969
CEA15943.1
Phosphoglucomutase; High confidence in function and specificity.
 
 
 0.967
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.966
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 
 0.963
pfkA2
6-phosphofructokinase 2; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 0.962
pfkA3
6-phosphofructokinase 3; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
 0.962
PFP-BETA2
Pyrophosphate-fructose 6-phosphate 1-phosphotransferase subunit beta 2; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 0.962
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.954
pyk
Pyruvate kinase; High confidence in function and specificity; Belongs to the pyruvate kinase family.
  
 
 0.951
CEA15640.1
Glyceraldehyde-3-phosphate dehydrogenase,cytosolic; High confidence in function and specificity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.949
Your Current Organism:
Fermentimonas caenicola
NCBI taxonomy Id: 1562970
Other names: CECT 8609, DSM 28696, F. caenicola, Fermentimonas caenicola Hahnke et al. 2016, LMG 28429, LMG:28429, Porphyromonadaceae bacterium ING2-E5B, strain E5B, strain ING2-E5B
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