Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMTAminomethyltransferase. (258 aa)    
Predicted Functional Partners:
ENSCCEP00000007779
annotation not available
 
 0.999
GLDC
Glycine dehydrogenase (decarboxylating), mitochondrial.
 
 0.999
DLD
Dihydrolipoyl dehydrogenase, mitochondrial.
  
 0.997
SHMT1
Serine hydroxymethyltransferase, cytosolic.
  
 0.987
MTHFD2
annotation not available
  
 
 0.983
MTHFD2L
Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2.
  
 
 0.983
MTHFR
Methylenetetrahydrofolate reductase isoform X1.
  
 
 0.972
GART
Trifunctional purine biosynthetic protein adenosine-3.
  
 
 0.970
LOC111928969
Trifunctional purine biosynthetic protein adenosine-3-like.
  
 
 0.970
AGXT
Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase.
  
 
 0.965
Your Current Organism:
Cyanistes caeruleus
NCBI taxonomy Id: 156563
Other names: Blaumeise, C. caeruleus, Parus caeruleus, blue tit
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