STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAS20031.1Putative DNA topoisomerase I, eukaryotic-like. (359 aa)    
Predicted Functional Partners:
EAS19378.1
Putative ATP-dependent DNA helicase.
    
 
 0.889
EAS19222.1
Topoisomerase IV. subunit B.
   
 
 0.861
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.861
rnhB
Ribonuclease HII, RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
    
 
 0.754
EAS18923.1
ATP-dependent dead/H DNA helicase.
    
 
 0.654
EAS20833.1
ATP-dependent DNA helicase RecQ.
    
 
 0.654
EAS19947.1
ATP-dependent DNA helicase RecQ.
    
 
 0.654
EAS19395.1
Hypothetical protein.
 
    0.552
lipB
Lipoate-protein ligase B, lipB; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
       0.551
EAS20934.1
ATP dependent DNA ligase.
 
 
 
 0.528
Your Current Organism:
Flavobacteria bacterium BBFL7
NCBI taxonomy Id: 156586
Other names: F. bacterium BBFL7, marine CFB-group bacterium BBFL7, marine bacterium BBFL7
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