STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mmc1_0253(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (753 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.944
Mmc1_0350
PFAM: Ppx/GppA phosphatase; KEGG: bfs:BF2669 putative phosphatase.
 
 
 0.931
Mmc1_2468
Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase; PFAM: TGS domain protein; KEGG: lil:LA3085 GTP pyrophosphokinase.
  
  
 
0.929
Mmc1_1432
Pyruvate kinase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate kinase; HpcH/HpaI aldolase; KEGG: ade:Adeh_4234 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.917
Mmc1_0728
PFAM: pyruvate kinase; KEGG: rru:Rru_A2465 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.915
Mmc1_3102
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: pae:PA0935 MazG protein.
  
 
 0.914
Mmc1_0641
SMART: guanylate kinase/L-type calcium channel region; KEGG: pac:PPA1190 guanylate kinase.
  
 
 0.913
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.912
Mmc1_0352
PFAM: RelA/SpoT domain protein; KEGG: sth:STH1636 putative GTP pyrophosphokinase.
    
 0.910
Mmc1_3489
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
     
 0.902
Your Current Organism:
Magnetococcus marinus
NCBI taxonomy Id: 156889
Other names: M. marinus MC-1, Magnetococcus marinus MC-1, Magnetococcus marinus str. MC-1, Magnetococcus marinus strain MC-1, Magnetococcus sp. MC-1
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