Mmc1_0773 protein (Magnetococcus marinus) - STRING interaction network

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Predicted Interactions

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Score

Mmc1_0773

Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bpa:BPP3781 LysR-family transcriptional regulator. (315 aa)

Predicted Functional Partners:

Mmc1_2381

0.653

Mmc1_3087

0.618

Mmc1_0774

0.611

Mmc1_0706

0.537

Mmc1_0449

0.499

Mmc1_0423

0.437

Mmc1_0775

0.417

Mmc1_0766

0.409

Your Current Organism:

Magnetococcus marinus

NCBI taxonomy Id: 156889
Other names: M. marinus MC-1, Magnetococcus marinus MC-1, Magnetococcus marinus str. MC-1, Magnetococcus marinus strain MC-1, Magnetococcus sp. MC-1

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
Mmc1_0423	Mmc1_0773	Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: mag:amb1137 AraC-type DNA-binding domain-containing protein.	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bpa:BPP3781 LysR-family transcriptional regulator.	0.437
Mmc1_0423	Mmc1_2381	Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: mag:amb1137 AraC-type DNA-binding domain-containing protein.	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bbr:BB2938 probable LysR-family transcriptional regulator.	0.520
Mmc1_0423	Mmc1_3087	Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: mag:amb1137 AraC-type DNA-binding domain-containing protein.	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2202 transcriptional regulator, LysR family.	0.488
Mmc1_0449	Mmc1_0706	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: tcx:Tcr_1555 transcriptional regulator, LysR family.	PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: noc:Noc_1604 glutamate synthase (ferredoxin).	0.537
Mmc1_0449	Mmc1_0773	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: tcx:Tcr_1555 transcriptional regulator, LysR family.	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bpa:BPP3781 LysR-family transcriptional regulator.	0.499
Mmc1_0706	Mmc1_0449	PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: noc:Noc_1604 glutamate synthase (ferredoxin).	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: tcx:Tcr_1555 transcriptional regulator, LysR family.	0.537
Mmc1_0706	Mmc1_0773	PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: noc:Noc_1604 glutamate synthase (ferredoxin).	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bpa:BPP3781 LysR-family transcriptional regulator.	0.537
Mmc1_0706	Mmc1_2381	PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: noc:Noc_1604 glutamate synthase (ferredoxin).	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bbr:BB2938 probable LysR-family transcriptional regulator.	0.537
Mmc1_0706	Mmc1_3087	PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: noc:Noc_1604 glutamate synthase (ferredoxin).	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2202 transcriptional regulator, LysR family.	0.537
Mmc1_0766	Mmc1_0773	Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: gsu:GSU0018 transcriptional regulator, GntR family/aminotransferase class-I.	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bpa:BPP3781 LysR-family transcriptional regulator.	0.409
Mmc1_0773	Mmc1_0423	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bpa:BPP3781 LysR-family transcriptional regulator.	Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: mag:amb1137 AraC-type DNA-binding domain-containing protein.	0.437
Mmc1_0773	Mmc1_0449	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bpa:BPP3781 LysR-family transcriptional regulator.	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: tcx:Tcr_1555 transcriptional regulator, LysR family.	0.499
Mmc1_0773	Mmc1_0706	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bpa:BPP3781 LysR-family transcriptional regulator.	PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: noc:Noc_1604 glutamate synthase (ferredoxin).	0.537
Mmc1_0773	Mmc1_0766	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bpa:BPP3781 LysR-family transcriptional regulator.	Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: gsu:GSU0018 transcriptional regulator, GntR family/aminotransferase class-I.	0.409
Mmc1_0773	Mmc1_0774	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bpa:BPP3781 LysR-family transcriptional regulator.	PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: neu:NE2510 NADH:flavin oxidoreductase/NADH oxidase.	0.611
Mmc1_0773	Mmc1_0775	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bpa:BPP3781 LysR-family transcriptional regulator.	PFAM: Pirin domain protein domain protein; Pirin domain protein; KEGG: gvi:glr2532 hypothetical protein; Belongs to the pirin family.	0.417
Mmc1_0773	Mmc1_2381	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bpa:BPP3781 LysR-family transcriptional regulator.	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bbr:BB2938 probable LysR-family transcriptional regulator.	0.653
Mmc1_0773	Mmc1_3087	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bpa:BPP3781 LysR-family transcriptional regulator.	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2202 transcriptional regulator, LysR family.	0.618
Mmc1_0774	Mmc1_0773	PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: neu:NE2510 NADH:flavin oxidoreductase/NADH oxidase.	Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bpa:BPP3781 LysR-family transcriptional regulator.	0.611
Mmc1_0774	Mmc1_0775	PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: neu:NE2510 NADH:flavin oxidoreductase/NADH oxidase.	PFAM: Pirin domain protein domain protein; Pirin domain protein; KEGG: gvi:glr2532 hypothetical protein; Belongs to the pirin family.	0.590

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Network Stats

number of nodes:

3

number of edges:

3

average node degree:

2

avg. local clustering coefficient:

1

expected number of edges:

2

PPI enrichment p-value:

0.211

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 110

1.55

3.37

2.00e-14

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

11 of 56

1.84

5.25

1.16e-17

GO:0019843

rRNA binding

10 of 45

1.9

5.25

3.40e-16

GO:0003723

RNA binding

11 of 123

1.5

3.19

9.30e-15

GO:0000049

tRNA binding

3 of 24

1.65

1.13

0.0042

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 60

1.81

5.17

3.58e-18

GO:0015935

Small ribosomal subunit

3 of 8

2.12

2.17

5.02e-05

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:34412707

(2021) The metabolic footprint of Clostridia and Erysipelotrichia reveals their role in depleting sugar alcohols in the cecum.

5 of 11

2.21

3.04

7.59e-07

PMID:37589280

(2023) L. rhamnosus CNCM I-3690 survival, adaptation, and small bowel microbiome impact in human.

6 of 23

1.97

2.98

2.51e-07

PMID:22043294

(2011) Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes.

4 of 9

2.2

2.22

4.62e-05

PMID:23342046

(2013) The genome sequences of Cellulomonas fimi and Cellvibrio gilvus reveal the cellulolytic strategies of two facultative anaerobes, transfer of Cellvibrio gilvus to the genus Cellulomonas, and proposal of Cellulomonas gilvus sp. nov.

5 of 32

1.74

1.92

4.62e-05

PMID:18851752

(2008) A simple, fast, and accurate method of phylogenomic inference.

5 of 34

1.72

1.9

4.62e-05

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:164

Small ribosomal subunit, and rRNA-binding

8 of 11

2.41

7.01

1.15e-15

CL:124

Structural constituent of ribosome

11 of 57

1.83

5.18

1.73e-17

CL:224

Mixed, incl. Translation elongation factor EF1B/ribosomal protein S6, and Ribosomal protein S5 domain 2-type fold, subgroup

3 of 6

2.25

2.16

6.91e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

cbut03010

Ribosome

11 of 56

1.84

5.4

1.69e-18

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

9 of 44

1.86

4.56

1.10e-13

GOCC:0015935

Small ribosomal subunit

4 of 8

2.25

3.07

7.38e-07

GOCC:0022627

Cytosolic small ribosomal subunit

3 of 7

2.18

2.17

5.82e-05

GOCC:0043229

Intracellular organelle

11 of 326

1.08

1.48

2.26e-10

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0699

rRNA-binding

10 of 43

1.92

5.49

6.60e-17

KW-0689

Ribosomal protein

11 of 59

1.82

5.18

5.70e-18

KW-0820

tRNA-binding

2 of 15

1.67

0.71

0.0401

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