SHJ57325.1 protein (Reichenbachiella agariperforans)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

SHJ57325.1

TonB-linked outer membrane protein, SusC/RagA family. (994 aa)

Predicted Functional Partners:

SHJ57295.1

0.932

SHJ57261.1

0.930

SHJ57232.1

0.915

SHJ57359.1

0.915

SHK67503.1

0.775

SHK67534.1

0.775

SHK67435.1

0.757

SHJ54263.1

0.752

SHJ57166.1

0.740

SHJ57388.1

0.738

Your Current Organism:

Reichenbachiella agariperforans

NCBI taxonomy Id: 156994
Other names: DSM 26134, JCM 11238, KMM 3525, NBRC 16625, R. agariperforans, Reichenbachia agariperforans, Reichenbachia agariperforans Nedashkovskaya et al. 2003, Reichenbachiella agariperforans (Nedashkovskaya et al. 2003) Nedashkovskaya et al. 2005 emend. Cha et al. 2011

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SHJ54263.1	SHJ57166.1	SAMN04488028_101451	SAMN04488028_101541	Starch-binding associating with outer membrane.	Enterochelin esterase.	0.489
SHJ54263.1	SHJ57232.1	SAMN04488028_101451	SAMN04488028_101543	Starch-binding associating with outer membrane.	Glycosyl hydrolase family 10.	0.733
SHJ54263.1	SHJ57261.1	SAMN04488028_101451	SAMN04488028_101544	Starch-binding associating with outer membrane.	Protein of unknown function.	0.743
SHJ54263.1	SHJ57295.1	SAMN04488028_101451	SAMN04488028_101545	Starch-binding associating with outer membrane.	Starch-binding associating with outer membrane.	0.740
SHJ54263.1	SHJ57325.1	SAMN04488028_101451	SAMN04488028_101546	Starch-binding associating with outer membrane.	TonB-linked outer membrane protein, SusC/RagA family.	0.752
SHJ54263.1	SHJ57359.1	SAMN04488028_101451	SAMN04488028_101547	Starch-binding associating with outer membrane.	Starch-binding associating with outer membrane.	0.753
SHJ54263.1	SHJ57388.1	SAMN04488028_101451	SAMN04488028_101548	Starch-binding associating with outer membrane.	TonB-linked outer membrane protein, SusC/RagA family.	0.788
SHJ54263.1	SHK67503.1	SAMN04488028_101451	SAMN04488028_10783	Starch-binding associating with outer membrane.	Starch-binding associating with outer membrane.	0.599
SHJ54263.1	SHK67534.1	SAMN04488028_101451	SAMN04488028_10784	Starch-binding associating with outer membrane.	Hypothetical protein.	0.605
SHJ57166.1	SHJ54263.1	SAMN04488028_101541	SAMN04488028_101451	Enterochelin esterase.	Starch-binding associating with outer membrane.	0.489
SHJ57166.1	SHJ57232.1	SAMN04488028_101541	SAMN04488028_101543	Enterochelin esterase.	Glycosyl hydrolase family 10.	0.814
SHJ57166.1	SHJ57261.1	SAMN04488028_101541	SAMN04488028_101544	Enterochelin esterase.	Protein of unknown function.	0.750
SHJ57166.1	SHJ57295.1	SAMN04488028_101541	SAMN04488028_101545	Enterochelin esterase.	Starch-binding associating with outer membrane.	0.748
SHJ57166.1	SHJ57325.1	SAMN04488028_101541	SAMN04488028_101546	Enterochelin esterase.	TonB-linked outer membrane protein, SusC/RagA family.	0.740
SHJ57166.1	SHJ57359.1	SAMN04488028_101541	SAMN04488028_101547	Enterochelin esterase.	Starch-binding associating with outer membrane.	0.720
SHJ57166.1	SHJ57388.1	SAMN04488028_101541	SAMN04488028_101548	Enterochelin esterase.	TonB-linked outer membrane protein, SusC/RagA family.	0.670
SHJ57166.1	SHK67503.1	SAMN04488028_101541	SAMN04488028_10783	Enterochelin esterase.	Starch-binding associating with outer membrane.	0.501
SHJ57232.1	SHJ54263.1	SAMN04488028_101543	SAMN04488028_101451	Glycosyl hydrolase family 10.	Starch-binding associating with outer membrane.	0.733
SHJ57232.1	SHJ57166.1	SAMN04488028_101543	SAMN04488028_101541	Glycosyl hydrolase family 10.	Enterochelin esterase.	0.814
SHJ57232.1	SHJ57261.1	SAMN04488028_101543	SAMN04488028_101544	Glycosyl hydrolase family 10.	Protein of unknown function.	0.937

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

36

PPI enrichment p-value:

0.000885

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000160

Phosphorelay signal transduction system

11 of 92

1.71

4.3

4.83e-16

GO:0018106

Peptidyl-histidine phosphorylation

3 of 31

1.61

1.09

0.0050

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000155

Phosphorelay sensor kinase activity

10 of 51

1.92

5.32

5.86e-16

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016021

Integral component of membrane

10 of 1095

0.59

0.48

0.00065

GO:0005886

Plasma membrane

8 of 841

0.61

0.45

0.0054

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3961

Phosphorelay sensor kinase activity

7 of 17

2.24

5.47

1.03e-12

CL:3959

Phosphorelay sensor kinase activity, and PAS domain

8 of 28

2.09

5.34

1.31e-13

CL:3945

Protein histidine kinase activity, and Diguanylate cyclase

9 of 54

1.85

4.51

1.30e-13

CL:3926

Signaling, and Diguanylate cyclase

11 of 142

1.52

3.21

3.34e-14

CL:3962

Phosphorelay sensor kinase activity, and Taxis

4 of 12

2.15

2.86

1.51e-06

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02020

Two-component system

11 of 396

1.07

1.46

2.42e-10

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0597

Phosphoprotein

8 of 72

1.67

3.24

1.85e-10

KW-0175

Coiled coil

8 of 484

0.85

0.76

0.00020

KW-0418

Kinase

4 of 123

1.14

0.74

0.0113

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00388

His Kinase A (phosphoacceptor) domain

9 of 33

2.06

5.88

1.02e-15

SM00387

Histidine kinase-like ATPases

9 of 40

1.98

5.44

2.35e-15

SM00448

cheY-homologous receiver domain

9 of 49

1.89

4.94

8.09e-15

SM00086

Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)

3 of 13

1.99

1.87

0.00017

SM00091

PAS domain

3 of 21

1.78

1.57

0.00048

(more ...)

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