STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHK19742.1ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. (849 aa)    
Predicted Functional Partners:
clpP
ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
  
 
 0.974
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.969
SHJ70082.1
ATP-dependent Clp protease adaptor protein ClpS; Belongs to the ClpS family.
  
 
 0.898
SHJ97316.1
HSP20 family protein; Belongs to the small heat shock protein (HSP20) family.
 
 
 0.854
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
  
 
 0.787
SHJ70742.1
Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity.
  
 
 0.773
SHK29599.1
DnaJ domain-containing protein.
  
 
 0.749
SHJ49335.1
Curved DNA-binding protein.
  
 
 0.735
SHJ61366.1
Hypothetical protein.
  
 
 0.730
SHJ97012.1
DnaJ domain-containing protein.
  
 
 0.730
Your Current Organism:
Reichenbachiella agariperforans
NCBI taxonomy Id: 156994
Other names: DSM 26134, JCM 11238, KMM 3525, NBRC 16625, R. agariperforans, Reichenbachia agariperforans, Reichenbachia agariperforans Nedashkovskaya et al. 2003, Reichenbachiella agariperforans (Nedashkovskaya et al. 2003) Nedashkovskaya et al. 2005 emend. Cha et al. 2011
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