STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHK43657.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1149 aa)    
Predicted Functional Partners:
SHK88080.1
Myxalamid-type polyketide synthase MxaB.
    
 0.937
SHK31944.1
BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase.
  
 
 0.926
SHK56808.1
Glutamate synthase (NADPH/NADH) large chain.
  
 
 0.919
accD
acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
 
   
 0.912
SHK59176.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
   
 0.912
SHK87262.1
acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.909
SHJ65111.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.907
SHK17524.1
propionyl-CoA carboxylase beta chain.
 
 0.886
SHK49687.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.882
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 0.880
Your Current Organism:
Reichenbachiella agariperforans
NCBI taxonomy Id: 156994
Other names: DSM 26134, JCM 11238, KMM 3525, NBRC 16625, R. agariperforans, Reichenbachia agariperforans, Reichenbachia agariperforans Nedashkovskaya et al. 2003, Reichenbachiella agariperforans (Nedashkovskaya et al. 2003) Nedashkovskaya et al. 2005 emend. Cha et al. 2011
Server load: low (22%) [HD]