STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFI81962.1Hexose kinase, 1-phosphofructokinase family. (307 aa)    
Predicted Functional Partners:
SFH86191.1
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family.
 
  
 0.963
SFJ57849.1
Phosphotransferase system, enzyme I, PtsI; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.908
SFJ57778.1
PTS system, fructose-specific IIA component/PTS system, nitrogen regulatory IIA component.
 
 
 0.903
SFI00649.1
PTS system, nitrogen regulatory IIA component.
 
 
 0.900
pfp-2
6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
     
 0.885
SFH80675.1
Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily.
   
 
  0.873
SFH54361.1
Endo-1,4-beta-xylanase, GH35 family.
  
  
 0.855
SFI07789.1
Ribose 5-phosphate isomerase B.
  
 
 0.855
SFI98910.1
Ribose 5-phosphate isomerase B.
  
 
 0.855
SFJ70220.1
Ribose 5-phosphate isomerase B.
  
 
 0.855
Your Current Organism:
Planctomicrobium piriforme
NCBI taxonomy Id: 1576369
Other names: DSM 26348, P. piriforme, Planctomicrobium piriforme Kulichevskaya et al. 2015, Planctomycetaceae bacterium P3, VKM B-2887, strain P3
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