STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WNK8Serine/threonine-protein kinase WNK8. (687 aa)    
Predicted Functional Partners:
LYK3
LysM domain receptor-like kinase 3.
    
 
0.529
CR513_60798
Subtilisin-like protease; Belongs to the peptidase S8 family.
    
 
 0.520
GT-1
Trihelix transcription factor GT-1.
      
 0.493
MED14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.474
EXPA7
Expansin; Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. Belongs to the expansin family. Expansin A subfamily.
    
 
 0.461
RPA1C
Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses.
      
 0.418
RPA1B
Replication protein A 70 kDa DNA-binding subunit B.
      
 0.418
NPF2.11-3
Protein NRT1/ PTR FAMILY 2.11.
      
 0.418
MED7B
Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery.
    
 
 0.412
Your Current Organism:
Mucuna pruriens
NCBI taxonomy Id: 157652
Other names: M. pruriens, Mucuna pruriens (L.) DC., Mucuna sp. MR-2013, Stizolobium pruriens, Stizolobium pruriens (L.) Medik.
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.