Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXB70347.1Pseudouridylate synthase; KEGG: lba:Lebu_2251 4.3e-112 RNA-binding S4 domain-containing protein; K06178 23S rRNA pseudouridine2605 synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the pseudouridine synthase RsuA family. (228 aa)    
Predicted Functional Partners:
KXB70346.1
Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
  
  
 0.788
der
Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.787
KXB70348.1
HAD phosphoserine phosphatase-like hydrolase, family IB; KEGG: bmd:BMD_2485 6.8e-20 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Psort location: Cytoplasmic, score: 8.96.
       0.696
cmk
Cytidylate kinase; KEGG: lba:Lebu_0694 4.2e-91 cytidylate kinase; K00945 cytidylate kinase; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.683
KXB70350.1
Hypothetical protein; KEGG: edi:EDI_341030 0.00025 intracellular protein transport protein USO1; Psort location: Cytoplasmic, score: 8.96.
   
 
 0.671
KXB70349.1
Hypothetical protein; KEGG: kpo:KPN2242_04180 4.0e-15 acyl carrier protein phosphodiesterase K08682; Psort location: Cytoplasmic, score: 8.96.
       0.648
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
   
 0.501
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
     0.483
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
 
    0.466
KXB70345.1
KEGG: hpo:HMPREF4655_20240 4.1e-68 mreB; rod shape-determining protein MreB K03569; Psort location: Cytoplasmic, score: 9.97.
       0.458
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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