Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KXB70094.1KEGG: lba:Lebu_1942 7.1e-167 UDP-glucose 4-epimerase; K01784 UDP-glucose 4-epimerase; Psort location: Cytoplasmic, score: 8.96; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (341 aa)    
Predicted Functional Partners:
GtaB_2
KEGG: lba:Lebu_1186 3.6e-140 UTP-glucose-1-phosphate uridylyltransferase; K00963 UTP--glucose-1-phosphate uridylyltransferase; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.946
glmU
UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
   
 0.870
KXB64575.1
Putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: lba:Lebu_0519 1.0e-174 mannose-1-phosphate guanylyltransferase (GDP); K00971 mannose-1-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 8.96.
    
 0.846
KXB70093.1
Putative thioredoxin; KEGG: suq:HMPREF0772_12088 4.3e-18 trxA; thioredoxin K03671; Psort location: Cytoplasmic, score: 9.97; Belongs to the thioredoxin family.
       0.555
KXB68668.1
KEGG: lba:Lebu_2210 1.9e-205 dTDP-glucose 4,6-dehydratase; K01710 dTDP-glucose 4,6-dehydratase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.522
KXB70095.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.82.
       0.480
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
  
  
 0.440
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.413
lpxA
acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
   
 
 0.408
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
     
 0.407
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
Server load: medium (64%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.