Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sigARNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (392 aa)    
Predicted Functional Partners:
KXB69919.1
KEGG: snc:HMPREF0837_11413 2.5e-08 rpoD; DNA-directed RNA polymerase sigma subunit RpoD K03086; Psort location: Cytoplasmic, score: 9.97.
 
  
  0.959
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family.
 
  
 0.958
SigA_1
RNA polymerase sigma factor RpoD family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 
0.909
KXB69916.1
KEGG: str:Sterm_2945 5.8e-14 hypothetical protein; K03060 DNA-directed RNA polymerase subunit omega.
   
 
 0.897
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.884
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.868
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.850
KXB70088.1
Cyclic nucleotide-binding domain protein; Psort location: Cytoplasmic, score: 8.96.
    
 
 0.708
KXB66239.1
Transcriptional regulator, effector binding domain protein; KEGG: pjd:Pjdr2_5110 0.0040 AraC family transcriptional regulator; Psort location: Cytoplasmic, score: 9.97.
    
 
 0.690
KXB62995.1
Glutathione S-transferase protein; KEGG: ctt:CtCNB1_0619 1.9e-38 GSH-dependent dehydroascorbate reductase; K00799 glutathione S-transferase; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.643
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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