| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| rplD | rplP | HMPREF3180_00343 | HMPREF3180_00337 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.995 |
| rplD | rplV | HMPREF3180_00343 | HMPREF3180_00339 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. | 0.994 |
| rplD | rpmC | HMPREF3180_00343 | HMPREF3180_00336 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | Ribosomal protein L29; KEGG: apb:SAR116_2399 1.2e-06 50S ribosomal protein L29 K02904; Belongs to the universal ribosomal protein uL29 family. | 0.992 |
| rplD | rpsC | HMPREF3180_00343 | HMPREF3180_00338 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.997 |
| rplD | rpsE | HMPREF3180_00343 | HMPREF3180_00327 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. | 0.997 |
| rplD | rpsH | HMPREF3180_00343 | HMPREF3180_00330 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. | 0.997 |
| rplD | rpsN | HMPREF3180_00343 | HMPREF3180_00331 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | Ribosomal protein S14p/S29e; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. | 0.996 |
| rplD | rpsO | HMPREF3180_00343 | HMPREF3180_00243 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.991 |
| rplD | rpsQ | HMPREF3180_00343 | HMPREF3180_00335 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.998 |
| rplD | rpsS | HMPREF3180_00343 | HMPREF3180_00340 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.997 |
| rplP | rplD | HMPREF3180_00337 | HMPREF3180_00343 | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.995 |
| rplP | rplV | HMPREF3180_00337 | HMPREF3180_00339 | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. | 0.997 |
| rplP | rpmC | HMPREF3180_00337 | HMPREF3180_00336 | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | Ribosomal protein L29; KEGG: apb:SAR116_2399 1.2e-06 50S ribosomal protein L29 K02904; Belongs to the universal ribosomal protein uL29 family. | 0.997 |
| rplP | rpsC | HMPREF3180_00337 | HMPREF3180_00338 | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.999 |
| rplP | rpsE | HMPREF3180_00337 | HMPREF3180_00327 | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. | 0.993 |
| rplP | rpsH | HMPREF3180_00337 | HMPREF3180_00330 | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. | 0.996 |
| rplP | rpsN | HMPREF3180_00337 | HMPREF3180_00331 | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | Ribosomal protein S14p/S29e; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. | 0.991 |
| rplP | rpsO | HMPREF3180_00337 | HMPREF3180_00243 | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.968 |
| rplP | rpsQ | HMPREF3180_00337 | HMPREF3180_00335 | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.997 |
| rplP | rpsS | HMPREF3180_00337 | HMPREF3180_00340 | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.997 |