| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB66203.1 | mraY | HMPREF3180_01031 | HMPREF3180_00176 | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.582 |
| KXB66203.1 | murD | HMPREF3180_01031 | HMPREF3180_00175 | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.572 |
| KXB66203.1 | uppP | HMPREF3180_01031 | HMPREF3180_00385 | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.923 |
| KXB69389.1 | KXB69390.1 | HMPREF3180_00383 | HMPREF3180_00384 | KEGG: lba:Lebu_2077 1.3e-238 aldehyde dehydrogenase; K00131 glyceraldehyde-3-phosphate dehydrogenase (NADP); Psort location: Cytoplasmic, score: 9.97. | Coproporphyrinogen dehydrogenase HemZ; KEGG: lba:Lebu_1915 6.2e-239 coproporphyrinogen III oxidase; K02495 oxygen-independent coproporphyrinogen III oxidase; Psort location: Cytoplasmic, score: 9.97. | 0.467 |
| KXB69389.1 | msrA-2 | HMPREF3180_00383 | HMPREF3180_01505 | KEGG: lba:Lebu_2077 1.3e-238 aldehyde dehydrogenase; K00131 glyceraldehyde-3-phosphate dehydrogenase (NADP); Psort location: Cytoplasmic, score: 9.97. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.665 |
| KXB69389.1 | uppP | HMPREF3180_00383 | HMPREF3180_00385 | KEGG: lba:Lebu_2077 1.3e-238 aldehyde dehydrogenase; K00131 glyceraldehyde-3-phosphate dehydrogenase (NADP); Psort location: Cytoplasmic, score: 9.97. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.479 |
| KXB69390.1 | KXB69389.1 | HMPREF3180_00384 | HMPREF3180_00383 | Coproporphyrinogen dehydrogenase HemZ; KEGG: lba:Lebu_1915 6.2e-239 coproporphyrinogen III oxidase; K02495 oxygen-independent coproporphyrinogen III oxidase; Psort location: Cytoplasmic, score: 9.97. | KEGG: lba:Lebu_2077 1.3e-238 aldehyde dehydrogenase; K00131 glyceraldehyde-3-phosphate dehydrogenase (NADP); Psort location: Cytoplasmic, score: 9.97. | 0.467 |
| KXB69390.1 | KXB69392.1 | HMPREF3180_00384 | HMPREF3180_00386 | Coproporphyrinogen dehydrogenase HemZ; KEGG: lba:Lebu_1915 6.2e-239 coproporphyrinogen III oxidase; K02495 oxygen-independent coproporphyrinogen III oxidase; Psort location: Cytoplasmic, score: 9.97. | Cof-like hydrolase; KEGG: cbk:CLL_A2915 7.1e-41 phosphatase YidA K07024; Psort location: Cytoplasmic, score: 8.96. | 0.491 |
| KXB69390.1 | uppP | HMPREF3180_00384 | HMPREF3180_00385 | Coproporphyrinogen dehydrogenase HemZ; KEGG: lba:Lebu_1915 6.2e-239 coproporphyrinogen III oxidase; K02495 oxygen-independent coproporphyrinogen III oxidase; Psort location: Cytoplasmic, score: 9.97. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.809 |
| KXB69392.1 | KXB69390.1 | HMPREF3180_00386 | HMPREF3180_00384 | Cof-like hydrolase; KEGG: cbk:CLL_A2915 7.1e-41 phosphatase YidA K07024; Psort location: Cytoplasmic, score: 8.96. | Coproporphyrinogen dehydrogenase HemZ; KEGG: lba:Lebu_1915 6.2e-239 coproporphyrinogen III oxidase; K02495 oxygen-independent coproporphyrinogen III oxidase; Psort location: Cytoplasmic, score: 9.97. | 0.491 |
| KXB69392.1 | uppP | HMPREF3180_00386 | HMPREF3180_00385 | Cof-like hydrolase; KEGG: cbk:CLL_A2915 7.1e-41 phosphatase YidA K07024; Psort location: Cytoplasmic, score: 8.96. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.491 |
| mraY | KXB66203.1 | HMPREF3180_00176 | HMPREF3180_01031 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.582 |
| mraY | murD | HMPREF3180_00176 | HMPREF3180_00175 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.925 |
| mraY | uppP | HMPREF3180_00176 | HMPREF3180_00385 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.924 |
| msrA-2 | KXB69389.1 | HMPREF3180_01505 | HMPREF3180_00383 | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | KEGG: lba:Lebu_2077 1.3e-238 aldehyde dehydrogenase; K00131 glyceraldehyde-3-phosphate dehydrogenase (NADP); Psort location: Cytoplasmic, score: 9.97. | 0.665 |
| msrA-2 | uppP | HMPREF3180_01505 | HMPREF3180_00385 | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.406 |
| murD | KXB66203.1 | HMPREF3180_00175 | HMPREF3180_01031 | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.572 |
| murD | mraY | HMPREF3180_00175 | HMPREF3180_00176 | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.925 |
| murD | uppP | HMPREF3180_00175 | HMPREF3180_00385 | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.457 |
| uppP | KXB66203.1 | HMPREF3180_00385 | HMPREF3180_01031 | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.923 |