Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
KXB69397.1DnaJ domain protein; Psort location: CytoplasmicMembrane, score: 9.82. (206 aa)    
Predicted Functional Partners:
KXB64520.1
KEGG: lba:Lebu_0381 0. pyruvate ferredoxin/flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 8.96.
   
 0.869
KXB67928.1
Tetratricopeptide repeat protein; KEGG: tet:TTHERM_01109810 5.8e-08 Tubulin-tyrosine ligase family protein; Psort location: Cytoplasmic, score: 8.96.
    
 0.642
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
  
 
 0.637
KXB69396.1
Hypothetical protein; Psort location: OuterMembrane, score: 9.52.
       0.634
KXB67966.1
Hypothetical protein; KEGG: pfa:PF08_0011 5.2e-07 leucine-tRNA ligase; K01869 leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 8.96.
  
 0.604
HscC
DnaK family protein; KEGG: bpy:Bphyt_7074 5.0e-95 2-alkenal reductase K04045; Psort location: Cytoplasmic, score: 9.97; Belongs to the heat shock protein 70 family.
  
 0.604
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.604
msrA-2
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.598
KXB69395.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
       0.594
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.583
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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