Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXB69111.1Erm Leader peptide; KEGG: fnu:FN0522 1.2e-06 exonuclease SbcC K03546; Psort location: CytoplasmicMembrane, score: 10.00. (863 aa)    
Predicted Functional Partners:
KXB69110.1
Hypothetical protein; KEGG: bpb:bpr_I2867 0.0066 two component system histidine kinase.
 
     0.881
KXB69109.1
LemA family protein; Psort location: Cytoplasmic, score: 8.96.
       0.742
KXB69192.1
Hypothetical protein; KEGG: edi:EDI_289500 6.0e-06 cysteine-rich protein.
 
     0.538
KXB69107.1
Hypothetical protein; KEGG: abe:ARB_00683 0.0093 ubiquitin C-terminal hydrolase, putative; K11835 ubiquitin carboxyl-terminal hydrolase 4/11/15; Psort location: CytoplasmicMembrane, score: 10.00.
       0.478
KXB69108.1
Hypothetical protein.
       0.478
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.478
KXB64652.1
ScpA/B protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.469
KXB69112.1
NmrA family protein; KEGG: ssr:SALIVB_0958 1.2e-79 ytfG; oxidoreductase ytfG; Psort location: Cytoplasmic, score: 8.96.
       0.465
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.417
leuS
leucine--tRNA ligase; KEGG: lba:Lebu_0511 0. leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
    0.407
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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