Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXB69009.1Chorismate binding enzyme; KEGG: lba:Lebu_0832 4.2e-217 anthranilate synthase; K01657 anthranilate synthase component I; Psort location: Cytoplasmic, score: 9.97. (450 aa)    
Predicted Functional Partners:
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 0.999
KXB69012.1
KEGG: lba:Lebu_0825 6.0e-115 Indole-3-glycerol phosphate synthase; K01609 indole-3-glycerol phosphate synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the TrpC family.
 
 0.999
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.980
trpF
KEGG: lba:Lebu_0824 1.3e-105 phosphoribosylanthranilate isomerase; K01817 phosphoribosylanthranilate isomerase; Psort location: Cytoplasmic, score: 8.96; Belongs to the TrpF family.
 
  
 0.976
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.969
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.966
PheA
Chorismate mutase; KEGG: lba:Lebu_1672 1.2e-182 chorismate mutase; K14170 chorismate mutase / prephenate dehydratase; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.955
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
 
    
 0.758
KXB69011.1
Hypothetical protein; KEGG: zin:ZICARI_100 9.6e-05 nuoJ; putative NADH:ubiquinone oxidoreductase, membrane subunit J; K00339 NADH-quinone oxidoreductase subunit J; Psort location: CytoplasmicMembrane, score: 10.00.
       0.705
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
  
 0.696
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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