Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KXB68806.1KEGG: lba:Lebu_0850 1.9e-205 hydroxymethylglutaryl-CoA reductase, degradative; K00054 hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (430 aa)    
Predicted Functional Partners:
KXB68807.1
KEGG: lba:Lebu_0852 1.7e-190 hydroxymethylglutaryl-CoA synthase; K01641 hydroxymethylglutaryl-CoA synthase; Psort location: Cytoplasmic, score: 8.96.
 
 0.998
KXB60734.1
Mevalonate kinase; KEGG: lba:Lebu_0142 3.2e-132 mevalonate kinase; K00869 mevalonate kinase; Psort location: Cytoplasmic, score: 8.96.
 0.995
KXB60735.1
KEGG: lba:Lebu_0141 2.1e-158 diphosphomevalonate decarboxylase; K01597 diphosphomevalonate decarboxylase.
 
  
 0.863
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
   
 0.816
KXB62165.1
KEGG: lba:Lebu_1674 1.2e-134 phosphomevalonate kinase; K00938 phosphomevalonate kinase; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.740
KXB66334.1
Putative acyl carrier protein; KEGG: lba:Lebu_0132 0. AMP-dependent synthetase and ligase; K01897 long-chain acyl-CoA synthetase; Psort location: CytoplasmicMembrane, score: 7.88.
  
 
 0.726
KXB61011.1
Putative geranyltranstransferase; KEGG: lba:Lebu_0467 4.5e-142 polyprenyl synthetase; K13789 geranylgeranyl diphosphate synthase, type II; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.476
KXB59745.1
ATPase, AAA family; KEGG: atm:ANT_16460 6.3e-72 putative ATPase; Psort location: CytoplasmicMembrane, score: 7.88.
    
 
 0.407
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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