Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (346 aa)    
Predicted Functional Partners:
KXB64392.1
biotin--[acetyl-CoA-carboxylase] ligase; KEGG: fnu:FN1921 1.7e-53 biotin operon repressor K03524; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.918
KXB63647.1
KEGG: lba:Lebu_0127 1.8e-97 biotin--acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.918
tdk
Thymidine kinase; KEGG: lba:Lebu_1391 1.4e-179 thymidine kinase; K00857 thymidine kinase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.892
argD
Aminotransferase, acetylornithine/succinylornithine family; KEGG: lba:Lebu_0636 2.6e-185 acetylornithine and succinylornithine aminotransferase; K00821 acetylornithine/N-succinyldiaminopimelate aminotransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
  
 0.865
KXB68827.1
BioY family protein; KEGG: apb:SAR116_1163 3.6e-30 biotin biosynthesis protein BioY K03523; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.683
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
     
 0.416
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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