| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB59899.1 | KXB68607.1 | HMPREF3180_02128 | HMPREF3180_00702 | Putative aspartate transaminase; KEGG: lba:Lebu_1442 9.1e-167 class I and II aminotransferase; K00841 aminotransferase; Psort location: Cytoplasmic, score: 9.97. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.947 |
| KXB59899.1 | dapA | HMPREF3180_02128 | HMPREF3180_01821 | Putative aspartate transaminase; KEGG: lba:Lebu_1442 9.1e-167 class I and II aminotransferase; K00841 aminotransferase; Psort location: Cytoplasmic, score: 9.97. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.413 |
| KXB59899.1 | lysA | HMPREF3180_02128 | HMPREF3180_01826 | Putative aspartate transaminase; KEGG: lba:Lebu_1442 9.1e-167 class I and II aminotransferase; K00841 aminotransferase; Psort location: Cytoplasmic, score: 9.97. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.429 |
| KXB61719.1 | KXB68607.1 | HMPREF3180_01745 | HMPREF3180_00702 | Amidohydrolase; KEGG: str:Sterm_1988 4.4e-119 amidohydrolase; Psort location: Cytoplasmic, score: 8.96. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.704 |
| KXB68607.1 | KXB59899.1 | HMPREF3180_00702 | HMPREF3180_02128 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | Putative aspartate transaminase; KEGG: lba:Lebu_1442 9.1e-167 class I and II aminotransferase; K00841 aminotransferase; Psort location: Cytoplasmic, score: 9.97. | 0.947 |
| KXB68607.1 | KXB61719.1 | HMPREF3180_00702 | HMPREF3180_01745 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | Amidohydrolase; KEGG: str:Sterm_1988 4.4e-119 amidohydrolase; Psort location: Cytoplasmic, score: 8.96. | 0.704 |
| KXB68607.1 | asd | HMPREF3180_00702 | HMPREF3180_02110 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.893 |
| KXB68607.1 | dapA | HMPREF3180_00702 | HMPREF3180_01821 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.646 |
| KXB68607.1 | dapB | HMPREF3180_00702 | HMPREF3180_00925 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.962 |
| KXB68607.1 | dapF | HMPREF3180_00702 | HMPREF3180_01822 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.530 |
| KXB68607.1 | glyA | HMPREF3180_00702 | HMPREF3180_01001 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.456 |
| KXB68607.1 | guaA | HMPREF3180_00702 | HMPREF3180_01046 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.652 |
| KXB68607.1 | lysA | HMPREF3180_00702 | HMPREF3180_01826 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.682 |
| KXB68607.1 | pheT | HMPREF3180_00702 | HMPREF3180_00879 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | KEGG: lba:Lebu_2176 0. phenylalanyl-tRNA synthetase subunit beta; K01890 phenylalanyl-tRNA synthetase beta chain; Psort location: Cytoplasmic, score: 9.97. | 0.501 |
| asd | KXB68607.1 | HMPREF3180_02110 | HMPREF3180_00702 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.893 |
| asd | dapA | HMPREF3180_02110 | HMPREF3180_01821 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.964 |
| asd | dapB | HMPREF3180_02110 | HMPREF3180_00925 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.540 |
| asd | dapF | HMPREF3180_02110 | HMPREF3180_01822 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.441 |
| asd | glyA | HMPREF3180_02110 | HMPREF3180_01001 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.464 |
| asd | lysA | HMPREF3180_02110 | HMPREF3180_01826 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.458 |