Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KXB68615.1KEGG: lba:Lebu_1756 3.6e-69 acetolactate synthase small subunit; K01653 acetolactate synthase I/III small subunit; Psort location: Cytoplasmic, score: 9.97. (162 aa)    
Predicted Functional Partners:
KXB68614.1
KEGG: lba:Lebu_1757 3.0e-255 acetolactate synthase large subunit; K01652 acetolactate synthase I/II/III large subunit; Psort location: Cytoplasmic, score: 9.97.
 
 0.999
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.996
IlvA1
KEGG: lba:Lebu_1758 2.6e-176 threonine dehydratase; K01754 threonine dehydratase; Psort location: Cytoplasmic, score: 9.97.
  
 0.986
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 0.969
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 
 0.968
KXB64520.1
KEGG: lba:Lebu_0381 0. pyruvate ferredoxin/flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.945
ilvD
KEGG: lba:Lebu_1760 1.1e-273 dihydroxy-acid dehydratase; K01687 dihydroxy-acid dehydratase; Psort location: Cytoplasmic, score: 9.97; Belongs to the IlvD/Edd family.
 
 
 0.938
PflB
KEGG: lba:Lebu_1913 0. formate acetyltransferase; K00656 formate C-acetyltransferase; Psort location: Cytoplasmic, score: 9.97.
     
  0.900
KXB67973.1
KEGG: lba:Lebu_0542 1.6e-162 transketolase; K00162 pyruvate dehydrogenase E1 component subunit beta; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.867
KXB68816.1
Putative D-lactate dehydrogenase; KEGG: lba:Lebu_0987 1.7e-174 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase; K03778 D-lactate dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
    
  0.813
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.