Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KXB68165.1Hypothetical protein; KEGG: edi:EDI_119900 0.0058 DNA double-strand break repair Rad50 ATPase. (176 aa)    
Predicted Functional Partners:
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
  
 0.669
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
  
 0.665
argH
KEGG: lba:Lebu_1184 1.7e-229 argininosuccinate lyase; K01755 argininosuccinate lyase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.659
argG
KEGG: lba:Lebu_0418 9.0e-199 argininosuccinate synthase; K01940 argininosuccinate synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.642
KXB69672.1
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
  
  
 0.608
argJ
Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
  
  
 0.600
KXB68164.1
Magnesium transporter; Acts as a magnesium transporter.
       0.510
SpeB
Agmatinase; KEGG: lba:Lebu_1823 6.4e-150 agmatinase; K01480 agmatinase; Psort location: Cytoplasmic, score: 8.96; Belongs to the arginase family.
  
 
 0.466
KXB69661.1
Putative glutamate synthase [NADPH], large subunit; KEGG: str:Sterm_2340 0. glutamate synthase K00265; Psort location: Cytoplasmic, score: 9.26.
  
  
 0.457
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.436
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
Server load: medium (42%) [HD]