Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KXB67966.1Hypothetical protein; KEGG: pfa:PF08_0011 5.2e-07 leucine-tRNA ligase; K01869 leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 8.96. (895 aa)    
Predicted Functional Partners:
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
  
 0.905
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.812
KXB67928.1
Tetratricopeptide repeat protein; KEGG: tet:TTHERM_01109810 5.8e-08 Tubulin-tyrosine ligase family protein; Psort location: Cytoplasmic, score: 8.96.
  
 0.781
KXB67939.1
SUF system FeS assembly protein, NifU family; KEGG: hbo:Hbor_34450 4.3e-07 cysteine desulfurase; Psort location: Cytoplasmic, score: 8.96.
  
 0.752
groS
Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
  
 
 0.746
LpdA
Dihydrolipoyl dehydrogenase; KEGG: lba:Lebu_0545 2.8e-243 dihydrolipoamide dehydrogenase; K00382 dihydrolipoamide dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
  
 0.745
KXB67967.1
Efflux transporter, RND family, MFP subunit; KEGG: edi:EDI_048590 7.9e-08 kinetochore protein NDC80; Psort location: Cytoplasmic, score: 8.96.
       0.732
msrA-2
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 0.689
KXB67959.1
DnaJ domain protein; KEGG: apb:SAR116_1614 1.6e-12 DnaJ family molecular chaperone K03686; Psort location: Cytoplasmic, score: 9.26.
  
 0.655
rplP
Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
   
 
 0.644
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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