| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB66571.1 | KXB66572.1 | HMPREF3180_01002 | HMPREF3180_01003 | VacJ-like protein; KEGG: ccv:CCV52592_0586 2.8e-21 S-adenosyl-L-methionine-dependent methyltransferase MraW K04754. | Hypothetical protein. | 0.873 |
| KXB66571.1 | KXB67955.1 | HMPREF3180_01002 | HMPREF3180_00819 | VacJ-like protein; KEGG: ccv:CCV52592_0586 2.8e-21 S-adenosyl-L-methionine-dependent methyltransferase MraW K04754. | KEGG: lba:Lebu_1882 2.8e-165 serine-type D-Ala-D-Ala carboxypeptidase; K07258 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6); Psort location: CytoplasmicMembrane, score: 9.97; Belongs to the peptidase S11 family. | 0.404 |
| KXB66571.1 | KXB69984.1 | HMPREF3180_01002 | HMPREF3180_00195 | VacJ-like protein; KEGG: ccv:CCV52592_0586 2.8e-21 S-adenosyl-L-methionine-dependent methyltransferase MraW K04754. | YihY family protein; KEGG: bhl:Bache_1924 4.5e-46 tRNA-processing RNAse BN K07058; Psort location: CytoplasmicMembrane, score: 10.00. | 0.505 |
| KXB66571.1 | glyA | HMPREF3180_01002 | HMPREF3180_01001 | VacJ-like protein; KEGG: ccv:CCV52592_0586 2.8e-21 S-adenosyl-L-methionine-dependent methyltransferase MraW K04754. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.628 |
| KXB66571.1 | rph | HMPREF3180_01002 | HMPREF3180_01000 | VacJ-like protein; KEGG: ccv:CCV52592_0586 2.8e-21 S-adenosyl-L-methionine-dependent methyltransferase MraW K04754. | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.555 |
| KXB66571.1 | smc | HMPREF3180_01002 | HMPREF3180_01004 | VacJ-like protein; KEGG: ccv:CCV52592_0586 2.8e-21 S-adenosyl-L-methionine-dependent methyltransferase MraW K04754. | RecF/RecN/SMC protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.498 |
| KXB66572.1 | KXB66571.1 | HMPREF3180_01003 | HMPREF3180_01002 | Hypothetical protein. | VacJ-like protein; KEGG: ccv:CCV52592_0586 2.8e-21 S-adenosyl-L-methionine-dependent methyltransferase MraW K04754. | 0.873 |
| KXB66572.1 | glyA | HMPREF3180_01003 | HMPREF3180_01001 | Hypothetical protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.628 |
| KXB66572.1 | rph | HMPREF3180_01003 | HMPREF3180_01000 | Hypothetical protein. | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.555 |
| KXB66572.1 | smc | HMPREF3180_01003 | HMPREF3180_01004 | Hypothetical protein. | RecF/RecN/SMC protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.498 |
| KXB67955.1 | KXB66571.1 | HMPREF3180_00819 | HMPREF3180_01002 | KEGG: lba:Lebu_1882 2.8e-165 serine-type D-Ala-D-Ala carboxypeptidase; K07258 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6); Psort location: CytoplasmicMembrane, score: 9.97; Belongs to the peptidase S11 family. | VacJ-like protein; KEGG: ccv:CCV52592_0586 2.8e-21 S-adenosyl-L-methionine-dependent methyltransferase MraW K04754. | 0.404 |
| KXB69984.1 | KXB66571.1 | HMPREF3180_00195 | HMPREF3180_01002 | YihY family protein; KEGG: bhl:Bache_1924 4.5e-46 tRNA-processing RNAse BN K07058; Psort location: CytoplasmicMembrane, score: 10.00. | VacJ-like protein; KEGG: ccv:CCV52592_0586 2.8e-21 S-adenosyl-L-methionine-dependent methyltransferase MraW K04754. | 0.505 |
| glyA | KXB66571.1 | HMPREF3180_01001 | HMPREF3180_01002 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | VacJ-like protein; KEGG: ccv:CCV52592_0586 2.8e-21 S-adenosyl-L-methionine-dependent methyltransferase MraW K04754. | 0.628 |
| glyA | KXB66572.1 | HMPREF3180_01001 | HMPREF3180_01003 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hypothetical protein. | 0.628 |
| glyA | rph | HMPREF3180_01001 | HMPREF3180_01000 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.717 |
| glyA | smc | HMPREF3180_01001 | HMPREF3180_01004 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | RecF/RecN/SMC protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.419 |
| rph | KXB66571.1 | HMPREF3180_01000 | HMPREF3180_01002 | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | VacJ-like protein; KEGG: ccv:CCV52592_0586 2.8e-21 S-adenosyl-L-methionine-dependent methyltransferase MraW K04754. | 0.555 |
| rph | KXB66572.1 | HMPREF3180_01000 | HMPREF3180_01003 | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | Hypothetical protein. | 0.555 |
| rph | glyA | HMPREF3180_01000 | HMPREF3180_01001 | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.717 |
| smc | KXB66571.1 | HMPREF3180_01004 | HMPREF3180_01002 | RecF/RecN/SMC protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | VacJ-like protein; KEGG: ccv:CCV52592_0586 2.8e-21 S-adenosyl-L-methionine-dependent methyltransferase MraW K04754. | 0.498 |
