Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
macBABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (230 aa)    
Predicted Functional Partners:
KXB64845.1
Efflux ABC transporter, permease protein; KEGG: bya:BANAU_1347 4.4e-48 yknZ; Macrolide export ATP-binding/permease protein macB K02004; Psort location: CytoplasmicMembrane, score: 10.00.
 
 0.997
KXB64843.1
Efflux transporter, RND family, MFP subunit; KEGG: pfe:PSF113_1858 5.9e-09 pyoverdine-specific efflux macA-like protein K13888; Psort location: CytoplasmicMembrane, score: 9.82; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.930
KXB59933.1
Lipoprotein releasing system, transmembrane protein, LolC/E family; KEGG: apb:SAR116_0522 2.3e-35 ABC transporter permease K09808; Psort location: CytoplasmicMembrane, score: 10.00.
 
 
 0.898
KXB64842.1
Hypothetical protein; KEGG: edi:EDI_341030 1.5e-08 intracellular protein transport protein USO1; Psort location: OuterMembrane, score: 9.49.
  
 
 0.577
KXB59926.1
Hypothetical protein.
   
 
 0.556
msrA-2
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.416
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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