Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXB64604.1KEGG: lba:Lebu_1250 1.2e-61 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; K00950 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; Psort location: Cytoplasmic, score: 9.97. (164 aa)    
Predicted Functional Partners:
FolP
KEGG: lba:Lebu_1243 1.4e-154 dihydropteroate synthase; K00796 dihydropteroate synthase; Psort location: Cytoplasmic, score: 9.97.
 
 0.999
KXB64603.1
KEGG: lba:Lebu_1251 5.0e-31 dihydroneopterin aldolase; K01633 dihydroneopterin aldolase; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.993
KXB64116.1
Protein FolC; KEGG: lba:Lebu_0534 5.9e-195 bifunctional folylpolyglutamate synthase/dihydrofolate synthase; K11754 dihydrofolate synthase / folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.668
AroF
3-deoxy-7-phosphoheptulonate synthase; KEGG: lba:Lebu_1998 4.7e-170 phospho-2-dehydro-3-deoxyheptonate aldolase; K03856 3-deoxy-7-phosphoheptulonate synthase; Psort location: Cytoplasmic, score: 9.97.
      0.665
KXB64676.1
Putative DHNTP pyrophosphohydrolase; KEGG: llk:LLKF_1182 1.3e-32 folQ; dihydroneopterin triphosphate pyrophosphohydrolase; Psort location: Cytoplasmic, score: 8.96.
 
   
 0.629
KXB62180.1
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.538
KXB69009.1
Chorismate binding enzyme; KEGG: lba:Lebu_0832 4.2e-217 anthranilate synthase; K01657 anthranilate synthase component I; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.488
ribBA
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.483
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
  
 0.464
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
     
 0.418
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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